Thiophenesulfonylurea derivatives

ABSTRACT

A novel thiophenesulfonylurea derivative having herbicidal activity, having the formula (I): ##STR1## wherein the substituents are herein described.

TECHNICAL FIELD

The present invention relates to novel thiophenesulfonylurea derivatives having agriculturally suitable for herbicidal activity.

BACKGROUND OF THE INVENTION

It is publicly well known that sulfonylurea derivatives have a herbicidal activity. Here are the formulas for the sulfonylureas.

1) U.S. Pat. No. 4,370,480 discloses the compound having the following formula ##STR2## wherein, R is H, alkyl, alkenyl, alkynyl or alkyl substituted with 1˜4 of F, Cl, Br, OCH₃, CN or CO₂ R¹, alkenyl substituted with 1˜3 atoms of Cl, cycloalkyl, cycloalkenyl, cycloalkyl substituted with CH₃, CH₂ CH₃, Cl, OCH₃, etc. or CO₂ R¹ ;

X is H, Cl, CH₃, OCH₃, etc.;

Y is H, Cl, C₁ -C₄ of alkyl, halogen, alkoxy or alkyl substituted with CN, etc.;

Z is CH.

2) U.S. Pat. No. 4,786,314 discloses the compound having the following formula ##STR3## wherein, R¹ is alkyl, alkenyl, halogen, NO₂, haloalkenyl, alkynyl, haloalkynyl, alkoxy, haloalkoxy, alkoxyalkyl, ##STR4## etc.; R² ##STR5## etc.; R⁸ is H, C₁ -C₄ alkyl, alkenyl, alkynyl, CH₂ CH₂ Cl, CH₂ CH₂ F, C₁ -C₂ alkyl substituted with OMe or SMe, or cycloalkyl.

3) U.S. Pat. No. 4,612,035 discloses the compound having the following formula ##STR6## wherein, L is phenyl, naphthyl, pyridine or thiophene having substitutent;

R¹ is ##STR7## R²⁵ is H or alkyl; R²⁶ is alkyl.

4) U.S. Pat. No. 4,659,369 discloses the compound having the following formula ##STR8## wherein, Q is Q-1, Q-2, Q-3 or Q-4 as followings. ##STR9## and then, R¹ is ##STR10## R³ is H, C₁ -C₃ of alkyl or C₁ -C₃ of alkoxy; R⁴ and R⁵ are respectively C₁ -C₂ of alkyl;

R⁶ and R⁷ are respectively H or C₁ -C₂ of alkyl;

a is O, S or NCH₃ ;

W₁ is O or s;

A is ##STR11## wherein, X¹ is CH₃, OCH₃, OEt or OCHF₂ ; Y¹ is O or CH₂ ;

Y² is H or CH₃.

5) Japanes Patent Laid-Opened So 61-22083 discloses the compound having the following formula ##STR12## wherein, R is H or alkyl group;

X and Y are respectively methyl or methoxy group;

A is N or CH.

As the above patents, many sulfonylurea herbicides have been known until recently.

Even with these herbicides, more and more weeds develop immunity forwards these herbicides and cause undesirable vegetations. Thus, continuous research is in demand to develop more effective and newer for a good harvest.

Therefore, the object of the present invention is to provide new thiophenesulfonylurea derivatives having a very prominent herbicidal activity with a good selectivity for various vegetations and agriculturally suitable herbicides for treatment of pre-emergence and/or post-emergence or plant growth regulants.

SUMMARY OF THE INVENTION

The present invention relates to novel thiophenesulfonylurea derivatives having the following general formula (I) ##STR13## wherein, P is P-1, P-2 or P-3 as followings ##STR14## wherein, R¹ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, CN, NO₂, C₁ -C₃ alkoxy, C₁ -C₃ haloalkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, SCHF₂, NH₂, NHCH₃, N(Me)₂, C₁ -C₂ alkyl substituted with C₁ -C₂ alkoxy, C₁ -C₄ haloalkoxy, SH, SCH₃, CN or OH; or CO₂ R^(III) ; and then R¹ is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy; R^(II) is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, or when taken together connecting R^(I) and R^(II) , --(CH₂)₃ --, --(CH₂)₄ --, --(CH₂)₅ -- or CH₂ CH₂ OCH₂ CH.sub. 2 --, may be formed; R^(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ alkyl substituted with 1˜3 halogens or cyano groups, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄ alkoxyalkyl;

R is ##STR15## wherein, a is O or S; R² is C₁ -C₆ alkyl substituted with 1˜3 halogens; R⁴ and R⁵ are respectively C₁ -C₄ of alkyl; and R⁶ and R⁷ are respectively H, C₁ -C₃ alkyl or C₁ -C₃ haloalkyl;

E is CH₂ single bond;

R³ is H or CH₃ ;

W is O or S;

A is A1, A2, A3, A4, A5, A6 or A7 as followings; ##STR16## wherein, X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl) amino or C₃ -C₅ cycloalkyl:

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloakylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₁ -C₄ haloalkyl, C₂ -C₄ alkynyl, azido, cyano, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, CH₂ OH, C₃ -C₅ cycloalkyl, C₃ -C₅ cycloalkoxy, C₂ -C₅ alkylthioalkoxy, ##STR17## m is 2 or 3; L¹ and L² are independently O or S;

R⁴ and R⁵ are independently C₁ -C₄ alkyl;

R⁸ is H or CH₃ ;

Z is CH, N, CCH₃ or CC₂ H₅ ;

Y¹ is O or CH₂ ;

X¹ is CH₃, OCH₃, OC₂ H₅ or OCHF₂ ;

Y² is CH₃, CH₂ CH₃, OCH₃, OCH₂ CH₃, SCH₃ or SCH₂ CH₃ ;

X² is CH₃, CH₂ CH₃, or CH₂ CF₃ ;

Y³ is H or CH₃ ;

X³ is CH₃ or OCH₃ ;

Y⁴ is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃ or Cl;

X⁴ is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃ or Cl;

and these may be an agriculturally suitable salt, and then,

(1) if X is Cl, Br, F or I, Z is CH and Y is OCH₃, OC₂ H₅, NCH₃ (OCH₃), NH₂, NHCH₃, N(CH₃)₂ or OCHF₂ ;

(2) if X or Y is OCHF₂, Z is CH;

(3) X⁴ and Y⁴ are not Cl simultaneously;

(4) if W is S, R³ is H, E is a single bond, A is A₁, Z is CH or N and, Y is CH₃, OCH₃, OCH₂ CH₃, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃, CH(OCH₃)₂ or ##STR18## (5) if a number of total carbon atoms of X and Y is more than 4, a number of carbon atoms of R² is 4 or less than 4.

DETAILED DESCRIPTION OF THE INVENTION

Among the definitions according to the present invention, the following terms have the following meanings:

a) "Alkyl" used ether alone or in compound word such as "alkylthio" or "haloalkyl" etc. denotes straight chain or branched alkyls such as methyl, ethyl, n-propyl, isopropyl or buthyl isomers.

b) "Alkoxy" denotes methoxy, ethoxy, n-propoxy, isopropoxy or butoxy isomers.

c) "Alkenyl" denotes straight chain or branched alkenes, for example, vinyl, 1-propenyl, 2-propenyl or butenyl, pentenyl, hexenyl or heptenyl isomers etc.

d) "Alkynyl" denotes straight chain or branched alkynyl such as ethynyl, 1-propynyl, 2-propynyl, or butynyl, pentynyl or hexynyl isomers.

e) "Halogen" used ether alone or in compound word "halo" denotes chlorine, fluorine, bromine or Iodine.

A preferred group of thiophenesulfonylurea derivatives having the formula(I) shown as the below, in view of easiness of synthesis and herbicidal activity, wherein

(1) R³ is H; W is O; and E is single bond;

(2) R¹ is H, F, Cl, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C_(1-C) ₂ alkoxy, C₁ -C₂ haloalkoxy, C₁ -C₂ alkylthio, CH₂ OCH₃, OR CH₂ SCH₃ ;

(3) X is CH₃, OCH₃, OCH₂ CH₃, Cl, F, Br, OCHF₂, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CF₃, CH₂ Cl or CH₂ Br; Y is H, C₁ -C₃ alkyl, OCH₃, OCH₂ CH₃, CH₂ OCH₃, NHCH₃, NCH₃ (OCH₃), N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OC₂ H₅, OCH₂ CH₂ OCH₃, CH₂ SCH₃, OCHF₂, SCHF₂, cyclopropyl, C.tbd.CH, or C .tbd.C--CH₃ ;

(4) R² is CH₂ F, CHF₂, CHFCl, CH₂ Cl, CH₂ Br, CHFCH₃, CH₂ CH₂ F, CH₂ CH₂ CH₂ F, CH₂ CH₂ Cl, CHClCH₃, CHCl₂, CHFCH₂ F, CHClCH₂ Cl, CHFCH₂ Cl, CH₂ CF₃ or CF(CH₃)₂ ;

(5) A is A₁ ; X is CH₃, OCH₃, OCH₂ CH₃, Cl or OCHF₂ ; Y is CH₃, C₂ H₅, OCH₃, CH₂ OCH₃, CH(OCH₃)₂, OCHF₂, NHCH₃, N(Me)₂ or cyclopropyl, and R¹ is H, CH₃ or OCH₃.

The novel compounds having the above formula(I) according to the present invention have a very strong herbicide activity and good selectivity for a useful vegetation.

The compounds of the present invention can be prepared by reactions as described in herein below.

The compounds of general formula(I) can be obtained by reacting the compounds having the following formula(II) with an amine compound of the following formula(III). ##STR19## wherein, ##STR20##

The above reaction may be carried out in solvent such as methylene chloride, dichloro ethane or chloroform, and then the solvent can be used with catalytic amount of base such as DABCO(1,4-diazabicyclo[5.4.0]undece-7-ene), DBU(1,8-diazabicyclo[5.4.0]undece-7-ene), etc.

The compounds of general formula(I) can be obtained by reacting the compounds having the following formula(IV) with a carbamate compound of the following formula(V). ##STR21##

The compounds of the above formula(II) can be manufactured by reacting sulfonamide with phosgene. ##STR22##

The thiophenesulfonamide compounds of the above formula(IV) may be prepared by the following reaction process. ##STR23## In the above reaction, L is leaving group such as OEt, NMe₂, or N(CH₃)OCH₃ and R, R¹ and R² are as the above defined.

Sulfonamide substituted at 2,3-position of the following formula(IV-b) can be obtained by the method 4 of the above, but 2,3-dibromothiophene is used as the starting material. ##STR24##

Sulfonamide of the following formula(IV-c) can be obtained by the following reaction process, and then 3-bromothiophene is used as the starting material. ##STR25##

The heterocyclic amine compound of formula(III) may be prepared by a skill person in this technical field from a method disclosed in literatures or the simple transformation of it.

For example, European Patent Application No. 84,244 (Pub. Jul. 27, 1983) and J. Am. Chem. Soc., 69,3072(1947) of W. Braker et al. discloses a method for preparing aminopyrimidine and triazine substituted with acetyl group. European patent No. 72,347 and U.S. Pat. Nos. 4,443,243/4,487,915 disclose a method for preparing aminopyrimidine and/or triazine substituted with haloalkyl such as OCHF₂, SCHF₂, OCH₂ CH₂ F anti OCH₂ CF₃ etc. and haloalkylthio as a substitution group.

European Patent No. 108,708, U.S. Pat. Nos. 4,515,626/4,600,428 disclose cyclopropylpyrimidine and/or triazine substituted with alkyl, haloalkyl, alkoxy, haloalkoxy, alkylamino, dialkylamino and alkoxyalkyl group etc.

European Patent No. 15,863 discloses a method for preparing the compound of the above formula(VI), as 5,6-dihydro-puro[2,3-d] pyrimidine-2-amine compounds and cyclopenta[dd]pyrimidine-2-amine compounds which A is A₂ ; and 6,7-dihydro-5H-pyrano-[2,3-d] pyrimidine-2-amine compound which A is A₃.

European Patent No. 46,677 discloses puro[2,3-d]pyridine-2-amine compounds which A is A₄ in the formula(VI), and European Patent No. 73,562 discloses heterocyclic compounds which A is A₅.

The compound of formula(VI) which A is A₆ can be prepared by European Patent No. 94,260. The compound of formula(VI) which A is A₇ can be manufactured by the method of European Patent No. 125,864.

Common methods for preparing aminopyridine and triazine compounds are arranged on the following literatures:

"The chemistry and Heterocyclic compounds", Series, Interscience Publishers, Inc., New York and London; "Pyrimidines", Vol. 16, D. J. Brown Ed.; "S-Triazines and Derivatives", Vol. 13, E. M. Smolin and L. Rapaport. Composition of triazine compounds is disclosed in F. C. Schaefer, U.S. Pat. No. 3,154,547 and K. R. Huffman and F. C. Schaefer, J. Org. Chem., 28, 1812(1963).

On the other hand, salts of the compound of the above formula(I) also are useful as herbicide, and they can be prepared by various methods according to prior art.

For example, metal salts of the compound can be prepared by reacting the above formula(I) compound with strong basic anion, e.g. alkali or alkaline earth metal solution having hydroxyl group, alkoxide or carbonate, and also quaternary amine salt alike.

A salt of the formula(I) compound may also be obtained by cation exchange. The cation exchange can be manufactured by directly reacting solution containing cation for exchange with solution of salt of formula(l), for example, solution of alkali metal or quaternary amine salt.

This method is useful when the desired salt is water insoluble, for example, copper salt is separated by filtering.

This ion exchange may be carried out by passing through a column of cation exchange resin with solution of salt of the formula(I), for example, alkaline metal or quarternary amine salt solution.

This method is useful when the desirable salt is water soluble, especially sodium, potassium or calcium salt.

The above manufacturing methods am summarized briefly, but the methods can be easily carried out by a skill person in this technical field of composition and manufacturing for sulfonyl urea or organic composition.

The compounds of the above general formula(I) according to the present invention are specified as the following Tables 1˜45;

                                      TABLE 1                                      __________________________________________________________________________      ##STR26##                                                                     R.sup.1                                                                              R.sup.2                                                                              R.sup.3                                                                           X       Y        mp (°C.)                                __________________________________________________________________________     H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                                                               191-194                                        H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               OCH.sub.3                                                                               185-189                                        H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               CH.sub.3 179-184                                        H     CH.sub.2 F                                                                           H  Cl      OCH.sub.3                                                                               182-185                                        H     CH.sub.2 F                                                                           H  Br      OCH.sub.3                                               H     CH.sub.2 F                                                                           H  H       CH.sub.3                                                H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 F                                                                           H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub. 3                                                                             CH(OCH.sub.3).sub.2                                     H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 F                                                                           H  C.sub.2 H.sub.5                                                                        OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CF.sub.2                                                                               OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  F       OCH.sub.3                                               H     CH.sub.2 F                                                                           H  I       OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 F                                                                           H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 F                                                                           H  Cl      OC.sub.2 H.sub.5                                        H     CH.sub.2 F                                                                           H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 F                                                                           H  OC.sub. 2 H.sub.5                                                                      CH.sub.2 SCH.sub.3                                      H     CH.sub.2 F                                                                           H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 F                                                                           H  Cl      OCF.sub.2 H                                             H     CH.sub.2 F                                                                           H  NH.sub.2                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 F                                                                           H  n-C.sub.3 H.sub.2                                                                      OCH.sub.3                                               H     CH.sub.2 F                                                                           H  NHCH.sub.3                                                                             OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              SCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              SCF.sub.2 H                                             H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.2 CCH                                           H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.2 CHCH.sub.2                                    H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CCH                                                     H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              N(CH.sub.3).sub.2                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              cyclopropyl                                             H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              NH.sub.2                                                H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CF.sub.3                                                H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.2 CH.sub.2 OCH.sub.3                            H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CHO                                                     H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              COCH.sub.3                                              H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH(SCH.sub.3)OC.sub.2 H.sub.5                           H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              C(CH.sub.3)(SCH.sub.3).sub.2                            H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              C(SC.sub.2 H.sub.5).sub.2                               H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              1,3-dioxolan-2-yl                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              2-methyl-1,3-                                                                  oxathiolan-2yl                                          H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              1,3-oxathian-2-yl                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              2-methyl-1,3-                                                                  dithian-2-yl                                            H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              4-methyl-1,3-                                                                  dioxolan-2-yl                                           H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              2-4-dimethyl-1,3-                                                              dithiolan-2-yl                                          H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                                  H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CCCH.sub.3                                              H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCF.sub.2 Br                                            H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              OC.sub.2 H.sub.5                                        H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               CH.sub.3                                                H     CHFCH.sub.3                                                                          H  Cl      OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  Br      OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               H                                                       H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              H                                                       H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHFCH.sub.3                                                                          H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHFCH.sub.3                                                                          H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CF.sub.3                                                                               OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  F       OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  I       OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHFCH.sub.3                                                                          H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHFCH.sub.3                                                                          H  Cl      OC.sub.2 H.sub.5                                        H     CHFCH.sub.3                                                                          H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHFCH.sub.3                                                                          H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHFCH.sub.3                                                                          H  Cl      OCF.sub.2 H                                             H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  Cl      OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  Br      OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               H                                                       H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub. 2 CH.sub.2 F                                                                 H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 CH.sub.2 F                                                                  H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CF.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  F       OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  I       OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  Cl      OC.sub.2 H.sub.5                                        H     CH.sub.2 CH.sub.2 F                                                                  H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 CH.sub.2 F                                                                  H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  Cl      OCF.sub.2 H                                             H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              OCH.sub.3                                                                               208-211                                        H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               OCH.sub.3                                                                               205-209                                        H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               CH.sub.3 203-206                                        H     CH.sub.2 Cl                                                                          H  Cl      OCH.sub.3                                                                               188-192                                        H     CH.sub.2 Cl                                                                          H  Br      OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               Cl       186-190                                        H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 Cl                                                                          H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                                                        175-186                                        H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 Cl                                                                          H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CF.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  F       OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  I       OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 Cl                                                                          H  Cl      OC.sub.2 H.sub.5                                                                        190-193                                        H     CH.sub.2 Cl                                                                          H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 Cl                                                                          H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 Cl                                                                          H  Cl      OCF.sub.2 H                                             H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               CH.sub.3                                                H     CHClCH.sub.3                                                                         H  Cl      OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  Br      OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               H                                                       H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              H                                                       H     CHClCH.sub. 3                                                                        H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHClCH.sub.3                                                                         H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHClCH.sub.3                                                                         H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CF.sub.3                                                                               OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  F       OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  I       OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.3 CHF.sub.2                                                                    CH.sub.3                                                H     CHClCH.sub.3                                                                         H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHClCH.sub.3                                                                         H  Cl      OC.sub.2 H.sub.5                                        H     CHClCH.sub.3                                                                         H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHClCH.sub.3                                                                         H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHClCH.sub.3                                                                         H  Cl      OCF.sub.2 H                                             H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               CH.sub.3                                                H     CH.sub.2 Br                                                                          H  Cl      OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  Br      OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               H                                                       H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 Br                                                                          H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 Br                                                                          H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CF.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  F       OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  I       OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 Br                                                                          H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 Br                                                                          H  Cl      OC.sub.2 H.sub.5                                        H     CH.sub.2 Br                                                                          H  OCH.sub.2 H.sub.5                                                                      NHCH.sub.3                                              H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 Br                                                                          H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 Br                                                                          H  Cl      CHF.sub.2 H                                             H     CF.sub.3                                                                             H  OCH.sub.3                                                                              OCH.sub.3                                                                               209-212                                        H     CF.sub.3                                                                             H  CH.sub.3                                                                               OCH.sub.3                                                                               194-197                                        H     CF.sub.3                                                                             H  CH.sub.3                                                                               CH.sub.3 193-196                                        H     CF.sub.3                                                                             H  Cl      OCH.sub.3                                                                               196-200                                        H     CHF.sub.2                                                                            H  Br      OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.3                                                                               H                                                       H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              H                                                       H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHF.sub.2                                                                            H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHF.sub.2                                                                            H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHF.sub.2                                                                            H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHF.sub.2                                                                            H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHF.sub.2                                                                            H  CF.sub.3                                                                               OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  F       OCH.sub.3                                               H     CHF.sub.2                                                                            H  I       OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHF.sub.2                                                                            H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHF.sub.2                                                                            H  Cl      OC.sub.2 H.sub.5                                        H     CHF.sub.2                                                                            H  OC.sub.2 H.sub.5                                                                       NHCH.sub. 3                                             H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHF.sub.2                                                                            H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHF.sub.2                                                                            H  Cl      OCF.sub.2 H                                             H     CHFCl H  OCH.sub.3                                                                              OCH.sub.3                                               H     CHFCl H  CH.sub.3                                                                               OCH.sub.3                                               H     CHFCl H  CH.sub.3                                                                               CH.sub.3                                                H     CHFCl H  Cl      OCH.sub.3                                               H     CHFCl H  Br      OCH.sub.3                                               H     CHFCl H  CH.sub.3                                                                               H                                                       H     CHFCl H  OCH.sub.3                                                                              H                                                       H     CHFCl H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHFCl H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHFCl H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHFCl H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHFCl H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHFCl H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHFCl H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHFCl H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHFCl H  CF.sub.3                                                                               OCH.sub.3                                               H     CHFCl H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHFCl H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHFCl H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHFCl H  F       OCH.sub.3                                               H     CHFCl H  I       OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHFCl H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHFCl H  Cl      OC.sub.2 H.sub.5                                        H     CHFCl H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CHFCl H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHFCl H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHFCl H  Cl      OCF.sub.2 H                                             H     CHFCl H  n-C.sub.3 H.sub.7                                                                      OCH.sub.3                                               H     CHFCl H  OCH.sub.3                                                                              NHCH.sub.3                                              H     CHFCl H  OCH.sub.3                                                                              N(CH.sub.3).sub.2                                       H     CHFCl H  OCH.sub.3                                                                              cyclopropyl                                             H     CHFCl H  OCH.sub.3                                                                              OCH.sub.2 CH.sub.2 OCH.sub.3                            H     CHFCl H  OCH.sub.2 H.sub.5                                                                      CH.sub.2 SCH.sub.3                                      H     CHFCl H  OCH.sub.3                                                                              CH(SCH.sub.3)OC.sub.2 H.sub.5                           H     CHFCl H  OCH.sub.3                                                                              CH(SC.sub.2 H.sub.5).sub.2                              H     CHFCl H  OCH.sub.3                                                                              1,3-dioxolan-2-yl                                       H     CHFCl H  OCH.sub.3                                                                              N(OCH.sub.3)CH.sub.3                                    H     CHFCl H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHFCl H  OCH.sub.3                                                                              CF.sub.3                                                5-F   CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 F                                                                           H  CH.sub.3                                                                               OCH.sub.3                                               5-Cl  CH.sub.2 F                                                                           H  CH.sub.3                                                                               CH.sub.3                                                5-Cl  CH.sub.2 F                                                                           H  Cl      OCH.sub.3                                               5-Br  CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-CH.sub.2 CN                                                                        CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-OCH.sub.3                                                                          CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-SCH.sub.3                                                                          CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-OCF.sub.2 H                                                                        CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 F                                                                           CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 F                                                                           CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Cl                                                                          CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               H     CHF.sub.2                                                                            CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 Br                                                                          CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 Cl                                                                          CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               __________________________________________________________________________

                                      TABLE 2                                      __________________________________________________________________________      ##STR27##                                                                     R.sup.1                                                                              R.sup.2                                                                              R.sup.3                                                                           X       Y        mp (°C.)                                __________________________________________________________________________     H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                                                               134-137                                        H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               OCH.sub.3                                                                               203-207                                        H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               CH.sub.3 205-210                                        H     CH.sub.2 F                                                                           H  Cl      OCH.sub.3                                                                               180-184                                        H     CH.sub.2 F                                                                           H  Br      OCH.sub.3                                               H     CH.sub.2 F                                                                           H  Cl      CH.sub.3                                                H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              H        193-198                                        H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 F                                                                           H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub. 2 F                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                                                        187-190                                        H     CH.sub.2 F                                                                           H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 F                                                                           H  C.sub.2 H.sub.5                                                                        OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CF.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  F       OCH.sub.3                                               H     CH.sub.2 F                                                                           H  I       OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 F                                                                           H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 F                                                                           H  Cl      OC.sub.2 H.sub.5                                                                        170-172                                        H     CH.sub.2 F                                                                           H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 F                                                                           H  OC.sub.2 H.sub.5                                                                       CH.sub.2 SCH.sub.3                                      H     CH.sub.2 F                                                                           H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 F                                                                           H  Cl      OCF.sub.2 H                                             H     CH.sub.2 F                                                                           H  NH.sub.2                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 F                                                                           H  n-C.sub.3 H.sub.7                                                                      OCH.sub.3                                               H     CH.sub.2 F                                                                           H  NHCH.sub.3                                                                             OCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              SCH.sub.3                                               H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              SCF.sub.2 H                                             H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.2 CCH                                           H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.2 CHCH.sub.2                                    H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CHCH                                                    H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              N(CH.sub.3).sub.2                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              cyclopropyl                                             H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              NH.sub.2                                                H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CF.sub.3                                                H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.2 CH.sub.2 OCH.sub.3                            H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CHO                                                     H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              COCH.sub.3                                              H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CH(SCH.sub.3)OC.sub.2 H.sub.5                           H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              C(CH.sub.3)(SCH.sub.3).sub.2                            H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              C(SC.sub.2 H.sub.5).sub.2                               H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              1,3-dioxolan-2-yl                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              2-methyl-1,3-                                                                  oxathiolan-2yl                                          H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              1,3-oxathian-2-yl                                       H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              2-methyl-1,3-                                                                  dithian-2-yl                                            H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              4-methyl-1,3-                                                                  dioxolan-2-yl                                           H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              2-4-dimethyl-1,3-                                                              dithiolan-2-yl                                          H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                                  H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              CCCH.sub.3                                              H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCF.sub.2 Br                                            H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              OC.sub.2 H.sub.5                                        H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               CH.sub.3                                                H     CHFCH.sub.3                                                                          H  Cl      OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  Br      OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               H                                                       H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              H                                                       H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHFCH.sub.3                                                                          H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHFCH.sub.3                                                                          H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHFCH.sub.3                                                                          H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CF.sub.3                                                                               OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  F       OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  I       OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHFCH.sub.3                                                                          H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHFCH.sub. 3                                                                         H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHFCH.sub.3                                                                          H  Cl      OC.sub.2 H.sub.5                                        H     CHFCH.sub.3                                                                          H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CHFCH.sub.3                                                                          H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHFCH.sub.3                                                                          H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHFCH.sub.3                                                                          H  Cl      OCF.sub.2 H                                             H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  Cl      OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  Br      OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               H                                                       H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 CH.sub.2 F                                                                  H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CF.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  F       OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  I       OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  Cl      OC.sub.2 H.sub.5                                        H     CH.sub.2 CH.sub.2 F                                                                  H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 CH.sub.2 F                                                                  H  OCH.sub. 3                                                                             CH.sub.2 SCH.sub.3                                      H     CH.sub.2 CH.sub.2 F                                                                  H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 CH.sub.2 F                                                                  H  Cl      OCF.sub.2 H                                             H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              OCH.sub.3                                                                               190-193                                        H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               OCH.sub.3                                                                               216-220                                        H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               CH.sub.3 213-217                                        H     CH.sub.2 Cl                                                                          H  Cl      OCH.sub.3                                                                               196-202                                        H     CH.sub.2 Cl                                                                          H  Br      OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               Cl       195-198                                        H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 Cl                                                                          H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                                                        198-203                                        H     CH.sub.2 Cl                                                                          H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 Cl                                                                          H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CF.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  F       OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  I       OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 Cl                                                                          H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 Cl                                                                          H  Cl      OC.sub.2 H.sub.5                                                                        193-196                                        H     CH.sub.2 Cl                                                                          H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 Cl                                                                          H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 Cl                                                                          H  Cl      OCF.sub.2 H                                             H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               CH.sub.3                                                H     CHClCH.sub.3                                                                         H  Cl      OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  Br      OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               H                                                       H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              H                                                       H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHClCH.sub.3                                                                         H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHClCH.sub.3                                                                         H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHClCH.sub.3                                                                         H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CF.sub.3                                                                               OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  F       OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  I       OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHClCH.sub.3                                                                         H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHClCH.sub.3                                                                         H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHClCH.sub.3                                                                         H  Cl      OC.sub.2 H.sub.5                                        H     CHClCH.sub. 3                                                                        H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CHClCH.sub.3                                                                         H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHClCH.sub.3                                                                         H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHClCH.sub.3                                                                         H  Cl      OCF.sub.2 H                                             H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               CH.sub.3                                                H     CH.sub.2 Br                                                                          H  Cl      OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  Br      OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               H                                                       H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              H                                                       H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CH.sub.2 Br                                                                          H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CH.sub.2 Br                                                                          H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CH.sub.2 Br                                                                          H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CF.sub. 3                                                                              OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  F       OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  I       OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CH.sub.2 Br                                                                          H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CH.sub.2 Br                                                                          H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CH.sub.2 Br                                                                          H  Cl      OC.sub.2 H.sub.5                                        H     CH.sub.2 Br                                                                          H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CH.sub.2 Br                                                                          H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CH.sub.2 Br                                                                          H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CH.sub.2 Br                                                                          H  Cl      OCF.sub.2 H                                             H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.3                                                                               OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.3                                                                               CH.sub.3                                                H     CHF.sub.2                                                                            H  Cl      OCH.sub.3                                               H     CHF.sub.2                                                                            H  Br      OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.3                                                                               H                                                       H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              H                                                       H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHF.sub.2                                                                            H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHF.sub.2                                                                            H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHF.sub.2                                                                            H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHF.sub.2                                                                            H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHF.sub.2                                                                            H  CF.sub.3                                                                               OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  F       OCH.sub.3                                               H     CHF.sub.2                                                                            H  I       OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHF.sub.2                                                                            H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHF.sub.2                                                                            H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHF.sub.2                                                                            H  Cl      OC.sub.2 H.sub.5                                        H     CHF.sub.2                                                                            H  OC.sub.2 H.sub.5                                                                       NHCH.sub. 3                                             H     CHF.sub.2                                                                            H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHF.sub.2                                                                            H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHF.sub.2                                                                            H  Cl      OCF.sub.2 H                                             H     CHFCl H  OCH.sub.3                                                                              OCH.sub.3                                               H     CHFCl H  CH.sub.3                                                                               OCH.sub.3                                               H     CHFCl H  CH.sub.3                                                                               CH.sub.3                                                H     CHFCl H  Cl      OCH.sub.3                                               H     CHFCl H  Br      OCH.sub.3                                               H     CHFCl H  CH.sub.3                                                                               H                                                       H     CHFCl H  OCH.sub.3                                                                              H                                                       H     CHFCl H  OCH.sub.3                                                                              CH.sub.2 OC.sub.2 H.sub.5                               H     CHFCl H  OCF.sub.2 H                                                                            OCH.sub.3                                               H     CHFCl H  OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                                     H     CHFCl H  CH.sub.3                                                                               OC.sub.2 H.sub.5                                        H     CHFCl H  CH.sub.3                                                                               CH.sub.2 OCH.sub.3                                      H     CHFCl H  OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                                      H     CHFCl H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHFCl H  OC.sub.2 H.sub.5                                                                       OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CF.sub.3                                                                     OCH.sub.3                                               H     CHFCl H  CF.sub.3                                                                               OCH.sub.3                                               H     CHFCl H  CH.sub.2 F                                                                             OCH.sub.3                                               H     CHFCl H  CH.sub.2 Cl                                                                            OCH.sub.3                                               H     CHF(3 H  CH.sub.2 Br                                                                            OCH.sub.3                                               H     CHFCl H  F       OCH.sub.3                                               H     CHFCl H  I       OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CH.sub.2 F                                                                   OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CH.sub.2 CF.sub.3                                                            OCH.sub.3                                               H     CHFCl H  OCH.sub.2 CHF.sub.2                                                                    CH.sub.3                                                H     CHFCl H  OCH.sub.2 CF.sub.3                                                                     CH.sub.3                                                H     CHFCl H  Cl      OC.sub.2 H.sub.5                                        H     CHFCl H  OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                              H     CHFCl H  OCH.sub.3                                                                              CH.sub.2 SCH.sub.3                                      H     CHFCl H  OCF.sub.2 H                                                                            CH.sub.3                                                H     CHFCl H  Cl      OCF.sub.2 H                                             H     CHFCl H  n-C.sub.3 H.sub.7                                                                      OCH.sub.3                                               H     CHFCl H  OCH.sub.3                                                                              NHCH.sub.3                                              H     CHFCl H  OCH.sub.3                                                                              N(CH.sub.3).sub.2                                       H     CHFCl H  OCH.sub.3                                                                              cyclopropyl                                             H     CHFCl H  OCH.sub.3                                                                              OCH.sub.2 CH.sub.2 OCH.sub.3                            H     CHFCl H  OC.sub.2 H.sub.5                                                                       CH.sub.2 SCH.sub.3                                      H     CHFCl H  OCH.sub.3                                                                              CH(SCH.sub.3)OC.sub.2 H.sub.5                           H     CHFCl H  OCH.sub.3                                                                              CH(SC.sub.2 H.sub.5).sub.2                              H     CHFCl H  OCH.sub.3                                                                              1,3-dioxolan-2-yl                                       H     CHFCl H  OCH.sub.3                                                                              N(OCH.sub.3)CH.sub.3                                    H     CHFCl H  OCH.sub.3                                                                              C.sub.2 H.sub.5                                         H     CHFCl H  OCH.sub.3                                                                              CF.sub.3                                                5-F   CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 Cl                                                                          H  OCH.sub.3                                                                              OCH.sub.3                                               5-Cl  CH.sub.2 F                                                                           H  CH.sub.3                                                                               OCH.sub.3                                               5-Cl  CH.sub.2 F                                                                           H  CH.sub.3                                                                               CH.sub.3                                                5-Cl  CH.sub.2 F                                                                           H  Cl      OCH.sub.3                                               5-Br  CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-CH.sub.2 CN                                                                        CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-OCH.sub.3                                                                          CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-SCH.sub.3                                                                          CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               5-OCF.sub.2 H                                                                        CH.sub.2 F                                                                           H  OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 F                                                                           CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 F                                                                           CH.sub.3                                                                          CH.sub.3                                                                               OCH.sub.3                                               H     CH.sub.2 Cl                                                                          CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               H     CHF.sub.2                                                                            CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               H     CH.sub.2 Br                                                                          CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               4-Cl  CH.sub.2 Cl                                                                          CH.sub.3                                                                          OCH.sub.3                                                                              OCH.sub.3                                               __________________________________________________________________________

                  TABLE 3                                                          ______________________________________                                          ##STR28##                                                                                                               mp                                   R.sup.1                                                                            R.sup.2   R.sup.3                                                                              X         Y           (°C.)                         ______________________________________                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.3   193-                                                                           196                                  H   CH.sub.2 F                                                                               H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.3  CH.sub.3    175-                                                                           178                                  H   CH.sub.2 F                                                                               H     Cl        OCH.sub.3   197-                                                                           201                                  H   CH.sub.2 F                                                                               H     Br        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     Cl        CH.sub.3    195-                                                                           199                                  H   CH.sub.2 F                                                                               H     OCH.sub.3 H                                                H   CH.sub. 2 F                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.3                        H   CH.sub.2 F                                                                               H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 F                                                                               H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 F                                                                               H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 F                                                                               H     C.sub.2 H.sub.5                                                                          OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     F         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     I         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 F                                                                               H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 F                                                                               H     Cl        OC.sub.2 H.sub.5                                                                           170-                                                                           174                                  H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         CH.sub.2 SCH.sub.3                               H   CH.sub.2 F                                                                               H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 F                                                                               H     Cl        OCF.sub.2 H                                      H   CH.sub.2 F                                                                               H     NH.sub.2  OC.sub.2 H.sub.5                                 H   CH.sub.2 F                                                                               H     n-C.sub.3 H.sub.7                                                                        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     NHCH.sub.3                                                                               OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 SCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 SCF.sub.2 H                                      H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.2 CCH                                    H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.2 CHCH.sub.2                             H   CH.sub.2 F                                                                               H     OCH.sub.3 CCH                                              H   CH.sub.2 F                                                                               H     OCH.sub.3 N(CH.sub.3).sub.2                                H   CH.sub.2 F                                                                               H     OCH.sub.3 cyclopropyl                                      H   CH.sub.2 F                                                                               H     OCH.sub.3 NH.sub.2                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 CF.sub.3                                         H   CH.sub. 2 F                                                                              H     OCH.sub.3 OCH.sub.2 CH.sub.2 OCH.sub.3                     H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 F                                                                               H     OCH.sub.3 CHO                                              H   CH.sub.2 F                                                                               H     OCH.sub.3 COCH.sub.3                                       H   CH.sub.2 F                                                                               H     OCH.sub.3 CH(SCH.sub.3)OC.sub.2 H.sub.5                    H   CH.sub.2 F                                                                               H     OCH.sub.3 C(CH.sub.3)(SCH.sub.3).sub.2                     H   CH.sub.2 F                                                                               H     OCH.sub.3 C(SC.sub.2 H.sub.5).sub.2                        H   CH.sub.2 F                                                                               H     OCH.sub.3 1,3-dioxolan-2-yl                                H   CH.sub.2 F                                                                               H     OCH.sub.3 2-methyl-1,3-                                                                  oxathiolan-2yl                                   H   CH.sub.2 F                                                                               H     OCH.sub.3 1,3-oxathian-2-yl                                H   CH.sub.2 F                                                                               H     OCH.sub.3 2-methyl-1,3-                                                                  dithian-2-yl                                     H   CH.sub.2 F                                                                               H     OCH.sub.3 4-methyl-1,3-                                                                  dioxolan-2-yl                                    H   CH.sub.2 F                                                                               H     OCH.sub.3 2-4-dimethyl-1,3                                                               dithiolan-2-yl                                   H   CH.sub.2 F                                                                               H     OCH.sub.3 N(OCH.sub.3)(CH.sub.3)                           H   CH.sub.2 F                                                                               H     OCH.sub.3 CCCH.sub.3                                       H   CH.sub.2 F                                                                               H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 F                                                                               H     OCH.sub.3 OCF.sub.2 Br                                     H   CHFCH.sub. 3                                                                             H     OCH.sub.3 OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     CH.sub.3  OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.3  CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     Br        OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.3  H                                                H   CHFCH.sub.3                                                                              H     OCH.sub.3 H                                                H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CHFCH.sub.3                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CHFCH.sub.3                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CHFCH.sub.3                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CF.sub.3  OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     F         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     I         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CHFCH.sub.3                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OCF.sub.2 H                                      H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     Br        OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  H                                                H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 H                                                H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 CH.sub.2 F                                                                      H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     F         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     I         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 CH.sub.2 F                                                                      H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OCF.sub.2 H                                      H   CH.sub.2 Cl                                                                              H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     Br        OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.3  H                                                H   CH.sub.2 Cl                                                                              H     OCH.sub.3 H                                                H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 Cl                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 Cl                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 Cl                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 Cl                                                                              H     OC.sub.2 H.sub. 5                                                                        OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     F         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     I         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 Cl                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OCF.sub.2 H                                      H   CH.sub.2 Br                                                                              H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     Br        OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  H                                                H   CH.sub.2 Br                                                                              H     OCH.sub.3 H                                                H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 Br                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 Br                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 Br                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     F         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     I         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 Br                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OCF.sub.2 H                                      ______________________________________                                    

                  TABLE 4                                                          ______________________________________                                          ##STR29##                                                                                                               mp                                   R.sup.1 R.sup.2   R.sup.3                                                                               X      Y         (°C.)                         ______________________________________                                         H       CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3 212-                                                                           214                                  H       CH.sub.2 F                                                                               H      OCH.sub.3                                                                             OCH.sub.3 225-                                                                           228                                  H       CH.sub.2 F                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CH.sub.2 F                                                                               H      OCH.sub.3                                                                             Cl                                             H       CH.sub.2 F                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CH.sub.2 Cl                                                                              H      CH.sub.3                                                                              OCH.sub.3 180-                                                                           185                                  H       CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                             OCH.sub.3 216-                                                                           219                                  H       CH.sub.2 Cl                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                         H       CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CH.sub.2 Br                                                                              H      CH.sub.3                                                                              OCH.sub.3                                      H       CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                      H       CH.sub.2 Br                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                         H       CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CF.sub.3  H      CH.sub.3                                                                              OCH.sub.3 205-                                                                           209                                  H       CF.sub.3  H      OCH.sub.3                                                                             OCH.sub.3 220-                                                                           223                                  H       CHF.sub.2 H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CHF.sub.2 H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                         H       CHF.sub.2 H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CH.sub.2 F                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                      H       CH.sub.2 Cl                                                                              CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                      H       CH.sub.2 F                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                      H       CH.sub.2 Br                                                                              CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub. 3                                     H       CH.sub.2 Cl                                                                              CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                      H       CH.sub.2 Br                                                                              CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                      H       CHF.sub.2 CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                      H       CHF.sub.2 CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                      H       CHF.sub.2 CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CH.sub.2 F                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CHFCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                      H       CHFCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                      H       CHFCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CHFCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                         H       CHFCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CHClCH.sub.3                                                                             H      CH.sub.3                                                                              OCH.sub.3                                      H       CHClCH.sub.3                                                                             H      OCH.sub.3                                                                             OCH.sub.3                                      H       CHClCH.sub.3                                                                             H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CHClCH.sub.3                                                                             H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                         H       CHClCH.sub.3                                                                             H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CH.sub.2 CH.sub.2 F                                                                      H      CH.sub.3                                                                              OCH.sub.3                                      H       CH.sub.2 CH.sub.2 F                                                                      H      OCH.sub.3                                                                             OCH.sub.3                                      H       CH.sub.2 CH.sub.2 F                                                                      H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     H       CH.sub.2 CH.sub.2 F                                                                      H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                         H       CH.sub.2 CH.sub.2 F                                                                      H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                              H       CHFCl     H      OCH.sub.3                                                                             OCH.sub.3                                      H       CHFCl     H      CH.sub.3                                                                              OCH.sub.3                                      H       CHFCl     H      CH.sub.3                                                                              CH.sub.3                                       H       CH.sub.2 Cl                                                                              H      Cl     OCH.sub.3 219-                                                                           222                                  H       CHFCl     H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                             H       CHFCl     H      CH.sub.3                                                                              OC.sub.2 H.sub.5                               H       CHFCl     H      CH.sub.2 Cl                                                                           OCH.sub.3                                      H       CHFCl     H      F      OCH.sub.3                                      H       CHFCl     H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                            H       CHFCl     H      OCHF.sub.2                                                                            OCH.sub.3                                      H       CHFCl     H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                      5-F     CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3                                      5-Cl    CH.sub.2 F                                                                               H      OCH.sub.3                                                                             CH.sub.3                                       5-Br    CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3                                      5-CH.sub.2 CN                                                                          CH.sub.2 F                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                      5-OCH.sub.3                                                                            CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3                                      5-SCH.sub.3                                                                            CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3                                      5-OCF.sub.2 H                                                                          CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3                                      5-Cl    CH.sub.2 Cl                                                                              H      CH.sub.3                                                                              OCH.sub.3                                      5-Cl    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                      5-Cl    CH.sub.2 F                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                     5-Cl    CH.sub.2 F                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                      ______________________________________                                    

                  TABLE 5                                                          ______________________________________                                          ##STR30##                                                                     R.sup.1                                                                             R.sup.2   R.sup.3                                                                               X       Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F                                                                               H      CH.sub.3                                                                               OCH.sub.3 185-189                                H    CH.sub.2 F                                                                               H      OCH.sub.3                                                                              OCH.sub.3 179-182                                H    CH.sub.2 F                                                                               H      OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                       H    CH.sub.2 F                                                                               H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F                                                                               H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                              H      CH.sub.3                                                                               OCH.sub.3 173-177                                H    CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                              OCH.sub.3 186-190                                H    CH.sub.2 Cl                                                                              H      OC.sub.2 H.sub.5                                                                       Cl        186-188                                H    CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                              H      CH.sub.3                                                                               OCH.sub.3                                        H    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              H      OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                       H    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CHF.sub.2 H      CH.sub.3                                                                               OCH.sub.3                                        H    CHF.sub.2 H      OCH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 H      OC.sub.3 H.sub.5                                                                       NHCH.sub.3                                       H    CHF.sub.2 H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2 H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CH.sub.2 F                                                                               CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                              OCH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                              CH.sub.3                                                                               OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                       H    CH.sub.2 F                                                                               CH.sub.3                                                                              OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                              H      CH.sub.3                                                                               OCH.sub.3                                        H    CHFCH.sub.3                                                                              H      OCH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                              H      OCH.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                              H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                              H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                             H      CH.sub.3                                                                               OCH.sub.3                                        H    CHClCH.sub.3                                                                             H      OCH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                             H      OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                       H    CHClCH.sub.3                                                                             H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                             H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                      H      CH.sub.3                                                                               OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H      OCH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H      OC.sub.2 H.sub.5                                                                       NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                      H      OCH.sub.3                                                                              N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                      H      OCH.sub.3                                                                              N(CH.sub.3).sub.2                                H    CHFCl     H      OCH.sub.3                                                                              OCH.sub.3                                        H    CHFCl     H      CH.sub.3                                                                               OCH.sub.3                                        H    CHFCl     H      CH.sub.3                                                                               CH.sub. 3                                        H    CHFCl     H      Cl      OCH.sub.3                                        H    CHFCl     H      OCH.sub.3                                                                              CH.sub.2 OCH.sub.3                               H    CHFCl     H      CH.sub.3                                                                               OC.sub.2 H.sub.5                                 H    CHFCl     H      CH.sub.2 Cl                                                                            OCH.sub.3                                        H    CHFCl     H      F       OCH.sub.3                                        H    CHFCl     H      OCH.sub.3                                                                              CH(OCH.sub.3).sub.2                              H    CHFCl     H      OCHF.sub.2                                                                             OCH.sub.3                                        H    CHFCl     H      C.sub.2 H.sub.5                                                                        OCH.sub.3                                        5-F  CH.sub.2 F                                                                               H      CH.sub.3                                                                               OCH.sub.3                                        ______________________________________                                    

                  TABLE 6                                                          ______________________________________                                          ##STR31##                                                                     R.sup.1                                                                             R.sup.2   R.sup.3                                                                               X      Y          mp                                     ______________________________________                                         H    CH.sub.2 F                                                                               H      CH.sub.3                                                                              OCH.sub.3  162-167                                H    CH.sub.2 F                                                                               H      OCH.sub.3                                                                             OCH.sub.3  195-198                                H    CH.sub.2 F                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                        H    CH.sub.2 F                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                            H    CH.sub.2 F                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                 H    CH.sub.2 Cl                                                                              H      CH.sub.3                                                                              OCH.sub.3                                         H    CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                         H    CH.sub.2 Cl                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                        H    CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                             N(OCH.sub. 3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                 H    CH.sub.2 Br                                                                              H      CH.sub.3                                                                              OCH.sub.3                                         H    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                         H    CH.sub.2 Br                                                                              H      OCH.sub.2 H.sub.5                                                                     NHCH.sub.3                                        H    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                            H    CH.sub.2 Br                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                 H    CHF.sub.2 H      CH.sub.3                                                                              OCH.sub.3                                         H    CHF.sub.2 H      OCH.sub.3                                                                             OCH.sub.3                                         H    CHF.sub.2 H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                        H    CHF.sub.2 H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                            H    CHF.sub.2 H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                 H    CH.sub.2 F                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                         H    CH.sub.2 Cl                                                                              CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                         H    CH.sub.2 F                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                         H    CH.sub.2 Br                                                                              CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                         H    CH.sub.2 Cl                                                                              CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                         H    CH.sub.2 Br                                                                              CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                         ______________________________________                                    

                  TABLE 7                                                          ______________________________________                                          ##STR32##                                                                     R.sup.1    R.sup.2    R.sup.3 X.sup.1 Y.sup.1                                                                             mp                                  ______________________________________                                         H          CH.sub.2 F H       CH.sub.3                                                                               O                                        H          CH.sub.2 F H       OCH.sub.3                                                                              O                                        H          CH.sub.2 F H       OC.sub.2 H.sub.5                                                                       O                                        H          CH.sub.2 F H       OCF.sub.2 H                                                                            O                                        H          CH.sub.2 F H       OCH.sub.3                                                                              CH.sub.2                                 H          CH.sub.2 Cl                                                                               H       CH.sub.3                                                                               O                                        H          CH.sub.2 Cl                                                                               H       OCH.sub.3                                                                              O                                        H          CH.sub.2 Br                                                                               H       CH.sub.3                                                                               O                                        H          CHFCH.sub.3                                                                               H       CH.sub.3                                                                               O                                        H          CHClCH.sub.3                                                                              H       CH.sub.3                                                                               O                                        5-CH.sub.3 CH.sub.2 F H       CH.sub.3                                                                               O                                        5-Cl       CH.sub.2 F H       CH.sub.3                                                                               O                                        5-CH.sub.3 CH.sub.2 F H       CH.sub.3                                                                               O                                        5-CH.sub.2 CN                                                                             CH.sub.2 F H       CH.sub.3                                                                               O                                        H          CH.sub.2 F CH.sub.3                                                                               CH.sub.3                                                                               O                                        H          CHF.sub.2  H       OCH.sub.3                                                                              O                                        ______________________________________                                    

                  TABLE 8                                                          ______________________________________                                          ##STR33##                                                                     R.sup.1    R.sup.2   R.sup.3 X.sup.1 Y.sub.1                                                                              mp                                  ______________________________________                                         H          CH.sub.2 F                                                                               H       CH.sub.3                                                                               O                                         H          CH.sub.2 F                                                                               H       OCH.sub.3                                                                              O                                         H          CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                       O                                         H          CH.sub.2 F                                                                               H       OCF.sub.2 H                                                                            O                                         H          CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.2                                  H          CH.sub.2 Cl                                                                              H       CH.sub.3                                                                               O                                         H          CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              O                                         H          CH.sub.2 Br                                                                              H       CH.sub.3                                                                               O                                         H          CHFCH.sub.3                                                                              H       CH.sub.3                                                                               O                                         H          CHClCH.sub.3                                                                             H       CH.sub.3                                                                               O                                         5-CH.sub.3 CH.sub.2 F                                                                               H       CH.sub.3                                                                               O                                         5-Cl       CH.sub. 2 F                                                                              H       CH.sub.3                                                                               O                                         5-CH.sub.3 CH.sub.2 F                                                                               H       CH.sub.3                                                                               O                                         5-CH.sub.2 CN                                                                             CH.sub.2 F                                                                               H       CH.sub.3                                                                               O                                         H          CH.sub.2 F                                                                               CH.sub.3                                                                               CH.sub.3                                                                               O                                         H          CHF.sub.2 H       OCH.sub.3                                                                              O                                         ______________________________________                                    

                  TABLE 9                                                          ______________________________________                                          ##STR34##                                                                     R.sup.1    R.sup.2     R.sup.3 X.sup.1  mp                                     ______________________________________                                         H          CH.sub.2 F  H       CH.sub.3                                        H          CH.sub.2 F  H       OCH.sub.3                                       H          CH.sub.2 F  H       OC.sub.2 H.sub.5                                H          CH.sub.2 F  H       OCF.sub.3 H                                     H          CH.sub.2 F  H       OCH.sub.3                                       H          CH.sub.2 F  H       CH.sub.3                                        H          CH.sub.2 Cl H       OCH.sub.3                                       H          CHFCl       H       OCH.sub.3                                       H          CHFCl       H       OCH.sub.3                                       H          CHFCH.sub.3 H       OCH.sub.3                                       H          CH.sub.2 F  H       OCH.sub.3                                       5-F        CH.sub.2 F  H       OCH.sub.3                                       5-OCH.sub.3                                                                               CH.sub.2 F  H       OCH.sub.3                                       5-Cl       CH.sub.2 F  H       OCH.sub.3                                       5-CH.sub.3 CH.sub. 2 F H       OCH.sub.3                                       5-CH.sub.2 CN                                                                             CH.sub.2 F  H       OCH.sub.3                                       H          CH.sub.2 Cl H       OCH.sub.3                                       H          CH.sub.2 Br H       OCH.sub.3                                       H          CH.sub.2 CH.sub.2 F                                                                        H       OCH.sub.3                                       H          CHClCH.sub.3                                                                               H       OCH.sub.3                                       H          CHF.sub.2   CH.sub.3                                                                               OCH.sub.3                                       5-Cl       CH.sub.2 F  H       OCH.sub.3                                       ______________________________________                                    

                  TABLE 10                                                         ______________________________________                                          ##STR35##                                                                     R.sup.1    R.sup.2    R.sup.3 X.sup.1                                                                               Y.sup.1                                                                              mp                                  ______________________________________                                         H          CH.sub.2 F H       CH.sub.3                                                                              O                                         H          CH.sub.2 F H       OCH.sub.3                                                                             O                                         H          CH.sub.2 F H       OC.sub.2 H.sub.5                                                                      O                                         H          CH.sub.2 F H       OCF.sub.2 H                                                                           O                                         H          CH.sub.2 F H       OCH.sub.3                                                                             CH.sub.2                                  H          CH.sub.2 Cl                                                                               H       C.sub.3                                                                               O                                         H          CH.sub.2 Cl                                                                               H       OCH.sub.3                                                                             O                                         H          CH.sub.2 Br                                                                               H       CH.sub.3                                                                              O                                         H          CHFCH.sub.3                                                                               H       CH.sub.3                                                                              O                                         H          CHClCH.sub.3                                                                              H       CH.sub.3                                                                              O                                         5-CH.sub.3 CH.sub.2 F H       CH.sub.3                                                                              O                                         5-Cl       CH.sub.2 F H       CH.sub.3                                                                              O                                         5-CH.sub.3 CH.sub.2 F H       CH.sub.3                                                                              O                                         5-CH.sub.2 CN                                                                             CH.sub.2 F H       CH.sub.3                                                                              O                                         H          CH.sub.2 F H       CH.sub.3                                                                              O                                         H          CHF.sub.2  H       OCH.sub.3                                                                             O                                         ______________________________________                                    

                  TABLE 11                                                         ______________________________________                                          ##STR36##                                                                     R.sup.1    R.sup.2   R.sup.3   X.sup.1                                                                               mp                                       ______________________________________                                         H          CH.sub.2 F                                                                               H         CH.sub.3                                        H          CH.sub.2 F                                                                               H         OCH.sub.3                                       H          CH.sub.2 F                                                                               H         OC.sub.2 H.sub.5                                H          CH.sub.2 F                                                                               H         OCF.sub.2 H                                     H          CH.sub.2 F                                                                               H         OCH.sub.3                                       H          CH.sub.2 F                                                                               H         CH.sub.3                                        H          CH.sub.2 Cl                                                                              H         OCH.sub.3                                       H          CHFCl     H         OCH.sub.3                                       H          CHFCl     H         OCH.sub.3                                       H          CHFCH.sub.3                                                                              H         OCH.sub.3                                       H          CH.sub.2 F                                                                               H         OCH.sub.3                                       5-F        CH.sub.2 F                                                                               H         OCH.sub.3                                       5-OCH.sub.3                                                                               CH.sub.2 F                                                                               H         OCH.sub.3                                       5-Cl       CH.sub.2 F                                                                               H         OCH.sub.3                                       5-CH.sub.3 CH.sub.2 F                                                                               H         OCH.sub.3                                       5-CH.sub.2 CN                                                                             CH.sub.2 F                                                                               H         OCH.sub.3                                       H          CH.sub.2 Cl                                                                              H         OCH.sub.3                                       H          CH.sub.2 Br                                                                              H         OCH.sub.3                                       H          CH.sub.2 CH.sub.2 F                                                                      H         OCH.sub.3                                       H          CHClCH.sub.3                                                                             H         OCH.sub.3                                       H          CHF.sub.2 H         OCH.sub.3                                       4-Cl       CH.sub.2 F                                                                               H         OCH.sub.3                                       ______________________________________                                    

                  TABLE 12                                                         ______________________________________                                          ##STR37##                                                                     R.sup.1    R.sup.2    R.sup.3 X.sup.1                                                                               mp                                        ______________________________________                                         H          CH.sub.2 F H       CH.sub.3                                         H          CH.sub.2 F H       OCH.sub.3                                        H          CH.sub.2 F H       OC.sub.2 H.sub.5                                 H          CH.sub.2 F H       OCF.sub.2 H                                      H          CH.sub.2 Cl                                                                               H       CH.sub.3                                         H          CH.sub.2 Cl                                                                               H       OCH.sub.3                                        H          CH.sub.2 Br                                                                               H       CH.sub.3                                         H          CHF.sub.2  H       CH.sub.3                                         H          CHF.sub.2  H       OCH.sub.3                                        H          CHFCH.sub.3                                                                               H       CH.sub.3                                         H          CHFCH.sub.3                                                                               H       OCH.sub.3                                        H          CHFCl      H       OCH.sub.3                                        H          CHFCl      H       CH.sub.3                                         5-Cl       CHFCl      H       CH.sub.3                                         5-Cl       CHFCl      H       OCH.sub.3                                        5-Cl       CH.sub.2 F H       CH.sub.3                                         5-Cl       CH.sub.2 F H       OCH.sub.3                                        5-CH.sub.3 CH.sub.2 F H       CH.sub.3                                         5-OCH.sub.3                                                                               CH.sub.2 F H       CH.sub.3                                         H          CH.sub.2 F CH.sub.3                                                                               CH.sub.3                                         H          CH.sub.2 F CH.sub.3                                                                               OCH.sub.3                                        H          CHClCH.sub.3                                                                              H       OCH.sub.3                                        H          CH.sub.2 CH.sub.2 F                                                                       H       OCH.sub.3                                        ______________________________________                                    

                  TABLE 13                                                         ______________________________________                                          ##STR38##                                                                     R.sup.1  R.sup.2   R.sup.3 X.sup.1 Y.sup.3                                                                              mp                                    ______________________________________                                         H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                       CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCF.sub.2 H                                                                            CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              H                                           H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               H                                           H        CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   H        CHFCl     H       OCH.sub.3                                                                              OCH.sub.3                                   H        CHFCl     H       OCH.sub.3                                                                              CH.sub.3                                    H        CHFCH.sub.3                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-F      CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-OCH.sub.3                                                                             CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 Br                                                                              H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                              CH.sub.3                                    H        CHClCH.sub.3                                                                             H       OCH.sub.3                                                                              CH.sub.3                                    H        CHF.sub.2 H       OCH.sub.3                                                                              CH.sub.3                                    5-Cl     CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    ______________________________________                                    

                  TABLE 14                                                         ______________________________________                                          ##STR39##                                                                     R.sup.1  R.sup.2  R.sup.3  X.sup.1 Y.sup.3                                                                              mp                                    ______________________________________                                         H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                       CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCF.sub.2 H                                                                            CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              H                                           H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               H                                           H        CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   H        CHFCl     H       OCH.sub.3                                                                              OCH.sub.3                                   H        CHFCl     H       OCH.sub.3                                                                              CH.sub.3                                    H        CHFCH.sub.3                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   H        CH.sub. 2 F                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   5-F      CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-OCH.sub.3                                                                             CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-CH.sub.2 CN                                                                           CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 Br                                                                              H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                              CH.sub.3                                    H        CHClCH.sub.3                                                                             H       OCH.sub.3                                                                              CH.sub.3                                    H        CHF.sub.2 H       OCH.sub.3                                                                              CH.sub.3                                    5-Cl     CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    ______________________________________                                    

                  TABLE 15                                                         ______________________________________                                          ##STR40##                                                                     R.sup.1  R.sup.2   R.sup.3 X.sup.1 Y.sup.3                                                                              mp                                    ______________________________________                                         H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                       CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCF.sub.2 H                                                                            CH.sub.3                                    H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              H                                           H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               H                                           H        CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   H        CHFCl     H       OCH.sub.3                                                                              OCH.sub.3                                   H        CHFCl     H       OCH.sub.3                                                                              CH.sub.3                                    H        CHFCH.sub.3                                                                              H       OCH.sub.3                                                                              OCH.sub.3                                   H        CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-F      CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-OCH.sub.3                                                                             CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       OCH.sub.3                                                                              OCH.sub.3                                   5-CH.sub.2 CN                                                                           CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 Br                                                                              H       OCH.sub.3                                                                              CH.sub.3                                    H        CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                              CH.sub.3                                    H        CHClCH.sub.3                                                                             H       OCH.sub.3                                                                              CH.sub.3                                    H        CHF.sub.2 H       OCH.sub.3                                                                              CH.sub.3                                    5-Cl     CH.sub.2 F                                                                               H       OCH.sub.3                                                                              CH.sub.3                                    ______________________________________                                    

                  TABLE 16                                                         ______________________________________                                          ##STR41##                                                                     R.sup.1  R.sup.2   R.sup.3 X.sup.2 Y.sup.2                                                                              mp                                    ______________________________________                                         H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               OC.sub.2 H.sub.5                            H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               SCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               SC.sub.2 H.sub.5                            H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               C.sub.2 H.sub.5                             H        CH.sub.2 F                                                                               H       C.sub.2 H.sub.5                                                                        OCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.2 CF.sub.3                                                                      OCH.sub.3                                   H        CH.sub.2 Cl                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CHFCl     H       CH.sub.3                                                                               OCH.sub.3                                   H        CHF.sub.2 H       CH.sub.3                                                                               OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-F      CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-OCH.sub.3                                                                             CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    5-CH.sub.2 CN                                                                           CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 Br                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                               OCH.sub.3                                   H        CHFCl     H       CH.sub.3                                                                               CH.sub.3                                    H        CHFCH.sub.3                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CHClCH.sub.3                                                                             H       CH.sub.3                                                                               OCH.sub.3                                   ______________________________________                                    

                  TABLE 17                                                         ______________________________________                                          ##STR42##                                                                     R.sup.1  R.sup.2   R.sup.3 X.sup.2 Y.sup.2                                                                              mp                                    ______________________________________                                         H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               OC.sub.2 H.sub.5                            H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               SCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               SC.sub.2 H.sub.5                            H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               C.sub.2 H.sub.5                             H        CH.sub.2 F                                                                               H       C.sub.2 H.sub.5                                                                        OCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.2 CF.sub.3                                                                      OCH.sub.3                                   H        CH.sub.2 Cl                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CHFCl     H       CH.sub.3                                                                               OCH.sub.3                                   H        CHF.sub.2 H       CH.sub.3                                                                               OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-F      CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-OCH.sub.3                                                                             CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    5-CH.sub.2 CN                                                                           CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 Br                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                               OCH.sub.3                                   H        CHFCl     H       CH.sub.3                                                                               CH.sub.3                                    H        CHFCH.sub.3                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CHClCH.sub.3                                                                             H       CH.sub.3                                                                               OCH.sub.3                                   ______________________________________                                    

                  TABLE 18                                                         ______________________________________                                          ##STR43##                                                                     R.sup.1  R.sup.2   R.sup.3 X.sup.2 Y.sup.2                                                                              mp                                    ______________________________________                                         H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               OC.sub.2 H.sub.5                            H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               SCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               SC.sub.2 H.sub.5                            H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    H        CH.sub.2 F                                                                               H       CH.sub.3                                                                               C.sub.2 H.sub.5                             H        CH.sub.2 F                                                                               H       C.sub.2 H.sub.5                                                                        OCH.sub.3                                   H        CH.sub.2 F                                                                               H       CH.sub.2 CF.sub.3                                                                      OCH.sub.3                                   H        CH.sub.2 Cl                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CHFCl     H       CH.sub. 3                                                                              OCH.sub.3                                   H        CHF.sub.2 H       CH.sub.3                                                                               OCH.sub.3                                   5-CH.sub.3                                                                              CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-F      CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-OCH.sub.3                                                                             CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   5-Cl     CH.sub.2 F                                                                               H       CH.sub.3                                                                               CH.sub.3                                    5-CH.sub.2 CN                                                                           CH.sub.2 F                                                                               H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 Br                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                               OCH.sub.3                                   H        CHFCl     H       CH.sub.3                                                                               CH.sub.3                                    H        CHFCH.sub.3                                                                              H       CH.sub.3                                                                               OCH.sub.3                                   H        CHClCH.sub.3                                                                             H       CH.sub.3                                                                               OCH.sub.3                                   ______________________________________                                    

                  TABLE 19                                                         ______________________________________                                          ##STR44##                                                                     R.sup.1    R.sup.2     R.sup.3  X.sup.3                                                                              mp                                       ______________________________________                                         H          CH.sub.2 F  H        CH.sub.3                                       H          CH.sub.2 F  H        OCH.sub.3                                      H          CH.sub.2 Cl H        CH.sub.3                                       H          CH.sub.2 Cl H        OCH.sub.3                                      H          CHF.sub.2   H        OCH.sub.3                                      H          CHF.sub.2   H        CH.sub.3                                       H          CHFCl       H        CH.sub.3                                       H          CHFCl       H        OCH.sub.3                                      H          CHFCH.sub.3 H        CH.sub.3                                       H          CHFCH.sub.3 H        OCH.sub.3                                      H          CHClCH.sub.3                                                                               H        OCH.sub.3                                      5-F        CH.sub.2 F  H        OCH.sub.3                                      5-Cl       CH.sub.2 F  H        OCH.sub.3                                      5-CH.sub.3 CH.sub.2 F  H        OCH.sub.3                                      5-OHC.sub.3                                                                               CH.sub.2 F  H        CH.sub.3                                       5-CH.sub.2 CN                                                                             CH.sub.2 F  H        CH.sub.3                                       5-Cl       CH.sub.2 F  H        OCH.sub.3                                      H          CH.sub.2 CH.sub.2 F                                                                        H        OCH.sub.3                                      H          CH.sub.2 F  CH.sub.3 OCH.sub.3                                      H          CH.sub.2 CH.sub.2 F                                                                        H        CH.sub.3                                       ______________________________________                                    

                  TABLE 20                                                         ______________________________________                                          ##STR45##                                                                     R.sup.1    R.sup.2     R.sup.3  X.sup.3                                                                              mp                                       ______________________________________                                         H          CH.sub.2 F  H        CH.sub.3                                       H          CH.sub.2 F  H        OCH.sub.3                                      H          CH.sub.2 Cl H        CH.sub.3                                       H          CH.sub.2 Cl H        OCH.sub.3                                      H          CHF.sub.2   H        OCH.sub.3                                      H          CHF.sub.2   H        CH.sub.3                                       H          CHFCl       H        CH.sub.3                                       H          CHFCl       H        OCH.sub.3                                      H          CHFCH.sub.3 H        CH.sub.3                                       H          CHFCH.sub.3 H        OCH.sub.3                                      H          CHClCH.sub.3                                                                               H        OCH.sub.3                                      5-F        CH.sub.2 F  H        OCH.sub.3                                      5-Cl       CH.sub.2 F  H        OCH.sub.3                                      5-CH.sub.3 CH.sub.2 F  H        CH.sub.3                                       5-OCH.sub.3                                                                               CH.sub.2 F  H        CH.sub.3                                       5-CH.sub.2 CN                                                                             CH.sub.2 F  H        CH.sub.3                                       5-Cl       CH.sub.2 F  H        OCH.sub.3                                      H          CH.sub.2 CH.sub.2 F                                                                        H        OCH.sub.3                                      H          CH.sub.2 F  CH.sub.3 OCH.sub.3                                      H          CH.sub.2 CH.sub.2 F                                                                        H        CH.sub.3                                       ______________________________________                                    

                  TABLE 21                                                         ______________________________________                                          ##STR46##                                                                     R.sup.1    R.sup.2     R.sup.3  X.sup.3                                                                              mp                                       ______________________________________                                         H          CH.sub.2 F  H        CH.sub.3                                       H          CH.sub.2 F  H        OCH.sub.3                                      H          CH.sub.2 Cl H        CH.sub.3                                       H          CH.sub.2 Cl H        OCH.sub.3                                      H          CHF.sub.2   H        OCH.sub.3                                      H          CHF.sub.2   H        CH.sub.3                                       H          CHFCl       H        CH.sub.3                                       H          CHFCl       H        OCH.sub.3                                      H          CHFCH.sub.3 H        CH.sub.3                                       H          CHFCH.sub.3 H        OCH.sub.3                                      H          CHClCH.sub.3                                                                               H        OCH.sub.3                                      5-F        CH.sub.2 F  H        OCH.sub.3                                      5-Cl       CH.sub.2 F  H        OCH.sub.3                                      5-CH.sub.3 CH.sub.2 F  H        CH.sub. 3                                      5-OCH.sub.3                                                                               CH.sub.2 F  H        CH.sub.3                                       5-CH.sub.2 CN                                                                             CH.sub.2 F  H        CH.sub.3                                       5-Cl       CH.sub.2 F  H        OCH.sub.3                                      H          CH.sub.2 CH.sub.2 F                                                                        H        OCH.sub.3                                      H          CH.sub.2 F  CH.sub.3 OCH.sub.3                                      H          CH.sub.2 CH.sub.2 F                                                                        H        CH.sub.3                                       ______________________________________                                    

                  TABLE 22                                                         ______________________________________                                          ##STR47##                                                                     R.sup.1 R.sup.2    R.sup.3                                                                               X.sup.4 Y.sup.4                                                                              Z.sup.1                                                                             mp                                ______________________________________                                         H       CH.sub.2 F H      CH.sub.3                                                                               CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      CH.sub.3                                                                               CH.sub.3                                                                             N                                      H       CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             N                                      H       CH.sub.2 F H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              OCH.sub.3                                                                            N                                      H       CH.sub.2 F H      Cl      CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              Cl    CH                                     H       CH.sub.2 F H      OC.sub.2 H.sub.5                                                                       CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                             N                                      H       CH.sub.2 F H      CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                            CH                                     H       CH.sub.2 F H      OC.sub.2 H.sub.5                                                                       OC.sub.2 H.sub.5                                                                     N                                      H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             N                                      H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              OCH.sub.3                                                                            N                                      H       CHF.sub.2  H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCl      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCH.sub.3                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHClCH.sub.3                                                                              H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-F     CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-CH.sub.3                                                                             CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-OCH.sub.3                                                                            CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-Cl    CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-CH.sub.2 CN                                                                          CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 CH.sub. 2 F                                                                      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 CH.sub.2 Cl                                                                      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCl      H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     ______________________________________                                    

                  TABLE 23                                                         ______________________________________                                          ##STR48##                                                                     R.sup.1 R.sup.2    R.sup.3                                                                               X.sup.4 Y.sup.4                                                                              Z.sup.1                                                                             mp                                ______________________________________                                         H       CH.sub.2 F H      CH.sub.3                                                                               CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      CH.sub.3                                                                               CH.sub.3                                                                             N                                      H       CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             N                                      H       CH.sub.2 F H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              OCH.sub.3                                                                            N                                      H       CH.sub.2 F H      Cl      CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              Cl    CH                                     H       CH.sub.2 F H      OC.sub.2 H.sub.5                                                                       CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                             N                                      H       CH.sub.2 F H      CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                            CH                                     H       CH.sub.2 F H      OC.sub.2 H.sub.5                                                                       OC.sub.2 H.sub.5                                                                     N                                      H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             N                                      H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              OCH.sub.3                                                                            N                                      H       CHF.sub.2  H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCl      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCH.sub.3                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHClCH.sub.3                                                                              H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-F     CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-CH.sub.3                                                                             CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-OCH.sub.3                                                                            CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-Cl    CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-CH.sub.2 CN                                                                          CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 CH.sub.2 Cl                                                                      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCl      H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     ______________________________________                                    

                  TABLE 24                                                         ______________________________________                                          ##STR49##                                                                     R.sup.1 R.sup.2    R.sup.3                                                                               X.sup.4 Y.sup.4                                                                              Z.sup.1                                                                             mp                                ______________________________________                                         H       CH.sub.2 F H      CH.sub.3                                                                               CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      CH.sub.3                                                                               CH.sub.3                                                                             N                                      H       CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             N                                      H       CH.sub.2 F H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     H       CH.sub.2 F H      OCH.sub.3                                                                              OCH.sub.3                                                                            N                                      H       CH.sub.2 F H      Cl      CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      OCH.sub. 3                                                                             Cl    CH                                     H       CH.sub.2 F H      OC.sub.2 H.sub.5                                                                       CH.sub.3                                                                             CH                                     H       CH.sub.2 F H      CH.sub.2 OCH.sub.3                                                                     CH.sub.3                                                                             N                                      H       CH.sub.2 F H      CH.sub.2 OCH.sub.3                                                                     OCH.sub.3                                                                            CH                                     H       CH.sub.2 F H      OC.sub.2 H.sub.5                                                                       OC.sub.2 H.sub.5                                                                     N                                      H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             N                                      H       CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                              OCH.sub.3                                                                            N                                      H       CHF.sub.2  H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCl      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCH.sub.3                                                                               H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHClCH.sub.3                                                                              H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-F     CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-CH.sub.3                                                                             CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-OCH.sub.3                                                                            CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-Cl    CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     5-CH.sub.2 CN                                                                          CH.sub.2 F H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CH.sub.2 CH.sub.2 Cl                                                                      H      OCH.sub.3                                                                              CH.sub.3                                                                             CH                                     H       CHFCl      H      OCH.sub.3                                                                              OCH.sub.3                                                                            CH                                     ______________________________________                                    

                  TABLE 25                                                         ______________________________________                                          ##STR50##                                                                     R.sup.1                                                                               R.sup.2   R.sup.3 W   X      Y     Z.sup.1                                                                             mp                              ______________________________________                                         H      CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 F                                                                               H       S   CH.sub.3                                                                              OCH.sub.3                                                                            N                                    H      CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            N                                    H      CH.sub.2 Cl                                                                              H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 Br                                                                              H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHF.sub.2 H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHFCl     H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHFCH.sub.3                                                                              H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHClCH.sub.3                                                                             H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   5-OCH.sub.3                                                                           CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   5-Cl   CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 F                                                                               CH.sub.3                                                                               S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             CH.sub.3                                                                             CH                                   ______________________________________                                    

                  TABLE 26                                                         ______________________________________                                          ##STR51##                                                                     R.sup.1                                                                               R.sup.2   R.sup.3                                                                               W    X     Y      Z.sup.1                                                                             mp                              ______________________________________                                         H      CH.sub.2 F                                                                               H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CH.sub.2 F                                                                               H      S    CH.sub.3                                                                             OCH.sub.3                                                                             N                                    H      CH.sub.2 F                                                                               H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             N                                    H      CH.sub.2 Cl                                                                              H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CH.sub.2 Br                                                                              H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CHF.sub.2 H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CHFCl     H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CHFCH.sub.3                                                                              H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CHClCH.sub. 3                                                                            H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   5-OCH.sub.3                                                                           CH.sub.2 F                                                                               H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   5-Cl   CH.sub.2 F                                                                               H      S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CH.sub.2 F                                                                               CH.sub.3                                                                              S    OCH.sub.3                                                                            OCH.sub.3                                                                             CH                                   H      CH.sub.2 F                                                                               H      S    OCH.sub.3                                                                            CH.sub.3                                                                              CH                                   ______________________________________                                    

                  TABLE 27                                                         ______________________________________                                          ##STR52##                                                                     R.sup.1                                                                               R.sup.2   R.sup.3 W   X      Y     Z.sup.1                                                                             mp                              ______________________________________                                         H      CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 F                                                                               H       S   CH.sub.3                                                                              OCH.sub.3                                                                            N                                    H      CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            N                                    H      CH.sub.2 Cl                                                                              H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 Br                                                                              H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHF.sub.2 H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHFCl     H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHFCH.sub.3                                                                              H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CHClCH.sub. 3                                                                            H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   5-OCH.sub.3                                                                           CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 F                                                                               CH.sub.3                                                                               S   OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                   H      CH.sub.2 F                                                                               H       S   OCH.sub.3                                                                             CH.sub.3                                                                             CH                                   ______________________________________                                    

                  TABLE 28                                                         ______________________________________                                          ##STR53##                                                                                                               mp                                   R.sup.1                                                                            R.sup.2   R.sup.3                                                                              X         Y           (°C.)                         ______________________________________                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.3   115-                                                                           117                                  H   CH.sub.2 F                                                                               H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.3  CH.sub.3    125-                                                                           130                                  H   CH.sub.2 F                                                                               H     Cl        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     Br        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     H         CH.sub.3                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 H                                                H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 F                                                                               H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 F                                                                               H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 F                                                                               H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 F                                                                               H     C.sub.2 H.sub.5                                                                          OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     F         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     I         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 F                                                                               H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 F                                                                               H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub. 5                                                                        NHCH.sub.3                                       H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         CH.sub.2 SCH.sub.3                               H   CH.sub.2 F                                                                               H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 F                                                                               H     Cl        OCF.sub.2 H                                      H   CH.sub.2 F                                                                               H     NH.sub.2  OC.sub.2 H.sub.5                                 H   CH.sub.2 F                                                                               H     n-C.sub.3 H.sub.7                                                                        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     NHCH.sub.3                                                                               OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 SCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 SCF.sub.2 H                                      H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.2 CCH                                    H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.2 CHCH.sub.2                             H   CH.sub.2 F                                                                               H     OCH.sub.3 CCH                                              H   CH.sub.2 F                                                                               H     OCH.sub.3 N(CH.sub.3).sub.2                                H   CH.sub.2 F                                                                               H     OCH.sub.3 cyclopropyl                                      H   CH.sub.2 F                                                                               H     OCH.sub.3 NH.sub.2                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 CF.sub.3                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.3 CH.sub.2 OCH.sub.3                     H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 F                                                                               H     OCH.sub.3 CHO                                              H   CH.sub.2 F                                                                               H     OCH.sub.3 COCH.sub.3                                       H   CH.sub.2 F                                                                               H     OCH.sub.3 CH(SCH.sub.3)OC.sub.2 H.sub.5                    H   CH.sub.2 F                                                                               H     OCH.sub.3 C(CH.sub.2)(SCH.sub.3).sub.2                     H   CH.sub.2 F                                                                               H     OCH.sub.3 C(SC.sub.2 H.sub.5).sub.2                        H   CH.sub.2 F                                                                               H     OCH.sub.3 1,3-dioxolan-2-yl                                H   CH.sub.2 F                                                                               H     OCH.sub.3 2-methyl-1,3-                                                                  oxathiolan-2yl                                   H   CH.sub.2 F                                                                               H     OCH.sub.3 1,3-oxathian-2-yl                                H   CH.sub.2 F                                                                               H     OCH.sub.3 2-methyl-1,3-                                                                  dithian-2-yl                                     H   CH.sub.2 F                                                                               H     OCH.sub.3 4-methyl-1,3-                                                                  dioxolan-2-yl                                    H   CH.sub.2 F                                                                               H     OCH.sub.3 2-4-dimethyl-1,3-                                                              dithiolan-2-yl                                   H   CH.sub.2 F                                                                               H     OCH.sub.3 N(OCH.sub.3)(CH.sub.3)                           H   CH.sub.2 F                                                                               H     OCH.sub.3 CCCH.sub.3                                       H   CH.sub.2 F                                                                               H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 F                                                                               H     OCH.sub.3 OCF.sub.2 Br                                     H   CHFCH.sub.3                                                                              H     OCH.sub.3 OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     CH.sub.3  OCH.sub.3                                        H   CF.sub.3  H     CH.sub.3  CH.sub.3    196-                                                                           199                                  H   CHFCH.sub.3                                                                              H     Cl        OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     Br        OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.3  H                                                H   CHFCH.sub.3                                                                              H     OCH.sub.3 H                                                H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CHFCH.sub.3                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CHFCH.sub.3                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CHFCH.sub.3                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CF.sub.3  OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     F         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     I         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CHFCH.sub.3                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OCF.sub.2 H                                      H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     Br        OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  H                                                H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 H                                                H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 CH.sub.2 F                                                                      H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     F         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     I         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CF.sub.3  H     Cl        OC.sub.2 H.sub.5                                                                           165-                                                                           167                                  H   CH.sub.2 CH.sub.2 F                                                                      H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OCF.sub.2 H                                      H   CF.sub.3  H     OCH.sub.3 OCH.sub.3   180-                                                                           182                                  H   CF.sub.3  H     CH.sub.3  OCH.sub.3   188-                                                                           191                                  H   CH.sub.2 Cl                                                                              H     CH.sub.3  CH.sub.3    166-                                                                           169                                  H   CF.sub.3  H     Cl        OCH.sub.3   173-                                                                           174                                  H   CH.sub.2 Cl                                                                              H     Br        OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.3  H                                                H   CH.sub.2 Cl                                                                              H     OCH.sub.3 H                                                H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 Cl                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 Cl                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 Cl                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 Cl                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     F         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     I         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 Cl                                                                              H     OCH.sub.2 H.sub.5                                                                        NHCH.sub.3                                       H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OCF.sub.2 H                                      H   CH.sub.2 Br                                                                              H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  OCH.sub. 3                                       H   CH.sub.2 Br                                                                              H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     Br        OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  H                                                H   CH.sub.2 Br                                                                              H     OCH.sub.3 H                                                H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 Br                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 Br                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     F         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     I         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 Br                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OCF.sub.2 H                                      ______________________________________                                    

                  TABLE 29                                                         ______________________________________                                          ##STR54##                                                                                                               mp                                   R.sup.1                                                                            R.sup.2   R.sup.3                                                                              X         Y           (°C.)                         ______________________________________                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.3   172-                                                                           175                                  H   CH.sub.2 F                                                                               H     CH.sub.3  OCH.sub.3   186-                                                                           187                                  H   CH.sub.2 F                                                                               H     CH.sub.3  CH.sub.3    190-                                                                           194                                  H   CH.sub.2 F                                                                               H     Cl        OCH.sub.3   148-                                                                           151                                  H   CH.sub.2 F                                                                               H     Br        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     Cl        CH.sub.3    172-                                                                           176                                  H   CH.sub.2 F                                                                               H     OCH.sub.3 H                                                H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 F                                                                               H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 F                                                                               H     CH.sub.3  OC.sub.2 H.sub.5                                                                           160-                                                                           163                                  H   CH.sub.2 F                                                                               H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 F                                                                               H     C.sub.2 H.sub.5                                                                          OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     F         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     I         OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 CHF.sub. 2                                                                     CH.sub.3                                         H   CH.sub.2 F                                                                               H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 F                                                                               H     Cl        OC.sub.2 H.sub.5                                                                           140-                                                                           145                                  H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 F                                                                               H     OC.sub.2 H.sub.5                                                                         CH.sub.2 SCH.sub.3                               H   CH.sub.2 F                                                                               H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 F                                                                               H     Cl        OCF.sub.2 H                                      H   CH.sub.2 F                                                                               H     NH.sub.2  OC.sub.2 H.sub.5                                 H   CH.sub.2 F                                                                               H     n-C.sub.3 H.sub.7                                                                        OCH.sub.3                                        H   CH.sub.2 F                                                                               H     NHCH.sub.3                                                                               OCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 SCH.sub.3                                        H   CH.sub.2 F                                                                               H     OCH.sub.3 SCF.sub.2 H                                      H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.2 CCH                                    H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.2 CHCH.sub.2                             H   CH.sub.2 F                                                                               H     OCH.sub.3 CCH                                              H   CH.sub.2 F                                                                               H     OCH.sub.3 N(CH.sub.3).sub.2                                H   CH.sub.2 F                                                                               H     OCH.sub.3 cyclopropyl                                      H   CH.sub.2 F                                                                               H     OCH.sub. 3                                                                               NH.sub.2                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 CF.sub.3                                         H   CH.sub.2 F                                                                               H     OCH.sub.3 OCH.sub.3 CH.sub.2 OCH.sub.3                     H   CH.sub.2 F                                                                               H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 F                                                                               H     OCH.sub.3 CHO                                              H   CH.sub.2 F                                                                               H     OCH.sub.3 COCH.sub.3                                       H   CH.sub.2 F                                                                               H     OCH.sub.3 CH(SCH.sub.3)OC.sub.2 H.sub.5                    H   CH.sub.2 F                                                                               H     OCH.sub.3 C(CH.sub.3)(SCH.sub.3).sub.2                     H   CH.sub.2 F                                                                               H     OCH.sub.3 C(SC.sub.2 H.sub.5).sub.2                        H   CH.sub.2 F                                                                               H     OCH.sub.3 1,3-dioxolan-2-yl                                H   CH.sub.2 F                                                                               H     OCH.sub.3 2-methyl-1,3-                                                                  oxathiolan-2yl                                   H   CH.sub.2 F                                                                               H     OCH.sub.3 1,3-oxathian-2-yl                                H   CH.sub.2 F                                                                               H     OCH.sub.3 2-methyl-1,3-                                                                  dithian-2-yl                                     H   CH.sub.2 F                                                                               H     OCH.sub.3 4-methyl-1,3-                                                                  dioxolan-2-yl                                    H   CH.sub.2 F                                                                               H     OCH.sub.3 2,4-dimethyl-1,3-                                                              dithiolan-2-yl                                   H   CH.sub.2 F                                                                               H     OCH.sub.3 N(OCH.sub.3)(CH.sub.3)                           H   CH.sub.2 F                                                                               H     OCH.sub.3 CCCH.sub.3                                       H   CH.sub.2 F                                                                               H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 F                                                                               H     OCH.sub.3 OCF.sub.2 Br                                     H   CHFCH.sub.3                                                                              H     OCH.sub.3 OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     CH.sub.3  OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.3  CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     Br        OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.3  H                                                H   CHFCH.sub.3                                                                              H     OCH.sub.3 H                                                H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CHFCH.sub.3                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CHFCH.sub.3                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CHFCH.sub.3                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CF.sub.3  OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     F         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     I         OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CHFCH.sub.3                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CHFCH.sub.3                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CHFCH.sub.3                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CHFCH.sub.3                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CHFCH.sub.3                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CHFCH.sub.3                                                                              H     Cl        OCF.sub.2 H                                      H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     Br        OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  Cl                                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 H                                                H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 CH.sub.2 F                                                                      H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     F         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     I         OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.2 H.sub.5                                                                        NHCH.sub.3                                       H   CH.sub.2 CH.sub.2 F                                                                      H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 CH.sub.2 F                                                                      H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 CH.sub.2 F                                                                      H     Cl        OCF.sub.2 H                                      H   CH.sub.2 Cl                                                                              H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.3  OCH.sub.3   157-                                                                           160                                  H   CH.sub.2 Cl                                                                              H     Cl        OCH.sub.3   156-                                                                           159                                  H   CH.sub.2 Cl                                                                              H     Br        OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.3  Cl          149-                                                                           153                                  H   CH.sub.2 Cl                                                                              H     OCH.sub.3 H                                                H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 Cl                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 Cl                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                                                           178-                                                                           180                                  H   CH.sub.2 Cl                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 Cl                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     F         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     I         OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OC.sub.2 H.sub.5                                                                           147-                                                                           149                                  H   CH.sub.2 Cl                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 Cl                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 Cl                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 Cl                                                                              H     Cl        OCF.sub.2 H                                      H   CH.sub.2 Br                                                                              H     OCH.sub.3 OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     Br        OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.3  H                                                H   CH.sub.2 Br                                                                              H     OCH.sub.3 H                                                H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 OC.sub.2 H.sub.5                        H   CH.sub.2 Br                                                                              H     OCF.sub.2 H                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH(OCH.sub.3).sub.2                              H   CH.sub.2 Br                                                                              H     CH.sub.3  OC.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     CH.sub.3  CH.sub.2 OCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 OCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCH.sub.3 C.sub.2 H.sub.5                                  H   CH.sub.2 Br                                                                              H     OC.sub.2 H.sub.5                                                                         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CF.sub.3                                                                       OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CF.sub.3  OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 F                                                                               OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 Cl                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     CH.sub.2 Br                                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     F         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     I         OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CH.sub.2 F                                                                     OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CH.sub.2 CF.sub.3                                                              OCH.sub.3                                        H   CH.sub.2 Br                                                                              H     OCH.sub.2 CHF.sub.2                                                                      CH.sub.3                                         H   CH.sub.2 Br                                                                              H     OCH.sub.2 CF.sub.3                                                                       CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OC.sub.2 H.sub.5                                 H   CH.sub.2 Br                                                                              H     OC.sub.2 H.sub.5                                                                         NHCH.sub.3                                       H   CH.sub.2 Br                                                                              H     OCH.sub.3 CH.sub.2 SCH.sub.3                               H   CH.sub.2 Br                                                                              H     OCF.sub.2 H                                                                              CH.sub.3                                         H   CH.sub.2 Br                                                                              H     Cl        OCF.sub.2 H                                      ______________________________________                                    

                  TABLE 30                                                         ______________________________________                                          ##STR55##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3 172-177                                H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3 183-187                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 31                                                         ______________________________________                                          ##STR56##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3 129-133                                H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3 139-142                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3 138-141                                H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3 133-136                                H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub. 5                                                                     NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub. 3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.3  H      OCH.sub.3                                                                             OCH.sub.3 165-166                                H    CHF.sub.3  H      CH.sub.3                                                                              OCH.sub. 3                                                                               174-176                                H    CHF.sub.3  H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 32                                                         ______________________________________                                          ##STR57##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3 153-157                                H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3 135-139                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3 138-140                                H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3 127-129                                H    CH.sub.2 Cl                                                                               H      OC.sub. 2 H.sub.5                                                                     NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub. 3                                                                             CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 33                                                         ______________________________________                                          ##STR58##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3 168-171                                H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3 145-148                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub. 3                                        H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                                      TABLE 34                                     __________________________________________________________________________      ##STR59##                                                                     R.sup.1                                                                           R.sup.2                                                                              R.sup.3                                                                            X        Y        mp (°C.)                                 __________________________________________________________________________     H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               OCH.sub.3                                                                               146-148                                         H  CH.sub.2 F                                                                           H   CH.sub.3 OCH.sub.3                                                                               145-148                                         H  CH.sub.2 F                                                                           H   CH.sub.3 CH.sub.3 177-178                                         H  CH.sub.2 F                                                                           H   Cl       OCH.sub.3                                                                               149-150                                         H  CH.sub.2 F                                                                           H   Br       OCH.sub.3                                                H  CH.sub.2 F                                                                           H   H        CH.sub.3                                                 H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               H                                                        H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CH.sub.2 OC.sub.2 H.sub.5                                H  CH.sub.2 F                                                                           H   OCF.sub.2 H                                                                             OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                      H  CH.sub.2 F                                                                           H   CH.sub.3 OC.sub.2 H.sub.5                                         H  CH.sub.2 F                                                                           H   CH.sub.3 CH.sub.2 OCH.sub.3                                       H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CH.sub.2 OCH.sub.3                                       H  CH.sub.2 F                                                                           H   C.sub.2 H.sub.5                                                                         OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OC.sub.2 H.sub.5                                                                        OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.2 CF.sub.3                                                                      OCH.sub.3                                                H  CH.sub.2 F                                                                           H   CF.sub.3 OCH.sub.3                                                H  CH.sub.2 F                                                                           H   CH.sub.2 F                                                                              OCH.sub.3                                                H  CH.sub.2 F                                                                           H   CH.sub.2 Cl                                                                             OCH.sub.3                                                H  CH.sub.2 F                                                                           H   CH.sub.2 Br                                                                             OCH.sub.3                                                H  CH.sub.2 F                                                                           H   F        OCH.sub.3                                                H  CH.sub.2 F                                                                           H   I        OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.2 CH.sub.2 F                                                                    OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.2 CH.sub.2 CF.sub.3                                                             OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.2 CHF.sub.2                                                                     CH.sub.3                                                 H  CH.sub.2 F                                                                           H   OCH.sub.2 CF.sub.3                                                                      CH.sub.3                                                 H  CH.sub.2 F                                                                           H   Cl       OC.sub.2 H.sub.5                                         H  CH.sub.2 F                                                                           H   OC.sub.2 H.sub.5                                                                        NHCH.sub.3                                               H  CH.sub.2 F                                                                           H   OC.sub.2 H.sub.5                                                                        CH.sub.2 SCH.sub.3                                       H  CH.sub.2 F                                                                           H   OCF.sub.2 H                                                                             CH.sub.3                                                 H  CH.sub.2 F                                                                           H   Cl       OCF.sub.2 H                                              H  CH.sub.2 F                                                                           H   NH.sub.2 OC.sub.2 H.sub.5                                         H  CH.sub.2 F                                                                           H   n-C.sub.3 H.sub.7                                                                       OCH.sub.3                                                H  CH.sub.2 F                                                                           H   NHCH.sub.3                                                                              OCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               SCH.sub.3                                                H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               SCF.sub.2 H                                              H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               OCH.sub.2 CCH                                            H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               OCH.sub.2 CHCH.sub.2                                     H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CCH                                                      H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               N(CH.sub.3).sub.2                                        H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               cyclopropyl                                              H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               NH.sub.2                                                 H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CF.sub.3                                                 H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               OCH.sub.2 CH.sub.2 OCH.sub.3                             H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CH.sub.2 SCH.sub.3                                       H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CHO                                                      H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               COCH.sub.3                                               H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CH(SCH.sub.3)OC.sub.2 H.sub.5                            H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               C(CH.sub.3)(SCH.sub.3).sub.2                             H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               C(SC.sub.2 H.sub.5).sub.2                                H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               1,3-dioxolan-2-yl                                        H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               2-methyl-1,3-                                                                  oxathiolan-2yl                                           H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               1,3-oxathian-2-yl                                        H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               2-methyl-1,3-                                                                  dithian-2-yl                                             H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               4-methyl-1,3-                                                                  dioxolan-2-yl                                            H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               2-4-dimethyl-1,3-                                                              dithiolan-2-yl                                           H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               N(OCH.sub.3)(CH.sub.3)                                   H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               CCCH.sub.3                                               H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               C.sub.2 H.sub.5                                          H  CH.sub.2 F                                                                           H   OCH.sub.3                                                                               OCF.sub.2 Br                                             H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               OC.sub.2 H.sub.5                                         H  CHFCH.sub.3                                                                          H   CH.sub.3 OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   CH.sub.3 CH.sub.3                                                 H  CHFCH.sub.3                                                                          H   Cl       OCH.sub.3                                                H  CHFCH.sub. 3                                                                         H   Br       OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   CH.sub.3 H                                                        H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               H                                                        H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               CH.sub.2 OC.sub.2 H.sub.5                                H  CHFCH.sub.3                                                                          H   OCO.sub.2 H                                                                             OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                      H  CHFCH.sub.3                                                                          H   CH.sub.3 OC.sub.2 H.sub.5                                         H  CHFCH.sub.3                                                                          H   CH.sub.3 CH.sub.2 OCH.sub.3                                       H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               CH.sub.2 OCH.sub.3                                       H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               C.sub.2 H.sub.5                                          H  CHFCH.sub.3                                                                          H   OC.sub.2 H.sub.5                                                                        OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   OCH.sub.2 CF.sub.3                                                                      OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   CF.sub.3 OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   CH.sub.2 F                                                                              OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   CH.sub.2 Cl                                                                             OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   CH.sub.2 Br                                                                             OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   F        OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   I        OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   OCH.sub.2 CH.sub.2 F                                                                    OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   OCH.sub.2 CH.sub.2 CF.sub.3                                                             OCH.sub.3                                                H  CHFCH.sub.3                                                                          H   OCH.sub.2 CHF.sub.2                                                                     CH.sub.3                                                 H  CHFCH.sub.3                                                                          H   OCH.sub.2 CF.sub.3                                                                      CH.sub.3                                                 H  CHFCH.sub.3                                                                          H   Cl       OC.sub.2 H.sub.5                                         H  CHFCH.sub.3                                                                          H   OC.sub.2 H.sub.5                                                                        NHCH.sub.3                                               H  CHFCH.sub.3                                                                          H   OCH.sub.3                                                                               CH.sub.2 SCH.sub.3                                       H  CHFCH.sub.3                                                                          H   OCF.sub.2 H                                                                             CH.sub.3                                                 H  CHFCH.sub.3                                                                          H   Cl       OCF.sub.2 H                                              H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.3 OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.3 CH.sub.3                                                 H  CH.sub.2 CH.sub.2 F                                                                  H   Cl       OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   Br       OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.3 H                                                        H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               H                                                        H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               CH.sub.2 OC.sub.2 H.sub.5                                H  CH.sub.2 CH.sub.2 F                                                                  H   OCF.sub.2 H                                                                             OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                      H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.3 OC.sub.2 H.sub.5                                         H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.3 CH.sub.2 OCH.sub.3                                       H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               CH.sub.2 OCH.sub.3                                       H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               C.sub.2 H.sub.5                                          H  CH.sub.2 CH.sub.2 F                                                                  H   OC.sub.2 H.sub.5                                                                        OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.2 CF.sub.3                                                                      OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CF.sub.3 OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.2 F                                                                              OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.2 Cl                                                                             OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   CH.sub.2 Br                                                                             OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   F        OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   I        OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.2 CH.sub.2 F                                                                    OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.2 CH.sub.2 CF.sub.3                                                             OCH.sub.3                                                H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.2 CHF.sub.2                                                                     CH.sub.3                                                 H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.2 CF.sub.3                                                                      CH.sub.3                                                 H  CH.sub.2 CH.sub.2 F                                                                  H   Cl       OC.sub.2 H.sub.5                                         H  CH.sub.2 CH.sub.2 F                                                                  H   OC.sub.2 H.sub.5                                                                        NHCH.sub.3                                               H  CH.sub.2 CH.sub.2 F                                                                  H   OCH.sub.3                                                                               CH.sub.2 SCH.sub.3                                       H  CH.sub.2 CH.sub.2 F                                                                  H   OCF.sub.2 H                                                                             CH.sub.3                                                 H  CH.sub.2 CH.sub.2 F                                                                  H   Cl       OCF.sub.2 H                                              H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CH.sub.3 OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CH.sub.3 CH.sub.3                                                 H  CH.sub.2 Cl                                                                          H   Cl       OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   Br       OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CH.sub.3 H                                                        H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               H                                                        H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               CH.sub.2 OC.sub.2 H.sub.5                                H  CH.sub.2 Cl                                                                          H   OCF.sub.2 H                                                                             OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                      H  CH.sub.2 Cl                                                                          H   CH.sub.3 OC.sub.2 H.sub.5                                         H  CH.sub.2 Cl                                                                          H   CH.sub.3 CH.sub.2 OCH.sub.3                                       H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               CH.sub.2 OCH.sub.3                                       H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               C.sub.2 H.sub.5                                          H  CH.sub.2 Cl                                                                          H   OC.sub.2 H.sub.5                                                                        OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   OCH.sub.2 CF.sub.3                                                                      OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CF.sub.3 OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CH.sub.2 F                                                                              OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CH.sub.2 Cl                                                                             OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   CH.sub.2 Br                                                                             OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   F        OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   I        OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   OCH.sub.2 CH.sub.2 F                                                                    OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   OCH.sub.2 CH.sub.2 CF.sub.3                                                             OCH.sub.3                                                H  CH.sub.2 Cl                                                                          H   OCH.sub.2 CHF.sub.2                                                                     CH.sub.3                                                 H  CH.sub.2 Cl                                                                          H   OCH.sub.2 CF.sub.3                                                                      CH.sub.3                                                 H  CH.sub.2 Cl                                                                          H   Cl       OC.sub.2 H.sub.5                                         H  CH.sub.2 Cl                                                                          H   OC.sub.2 H.sub.5                                                                        NHCH.sub.3                                               H  CH.sub.2 Cl                                                                          H   OCH.sub.3                                                                               CH.sub.2 SCH.sub.3                                       H  CH.sub.2 Cl                                                                          H   OCF.sub.2 H                                                                             CH.sub.3                                                 H  CH.sub.2 Br                                                                          H   Cl       OCF.sub.2 H.sub.5                                        H  CH.sub.2 Br                                                                          H   OCH.sub.3                                                                               OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CH.sub.3 OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CH.sub.3 CH.sub.3                                                 H  CH.sub.2 Br                                                                          H   Cl       OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   Br       OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CH.sub.3 H                                                        H  CH.sub.2 Br                                                                          H   OCH.sub.3                                                                               H                                                        H  CH.sub.2 Br                                                                          H   OCH.sub. 3                                                                              CH.sub.2 OC.sub.2 H.sub.5                                H  CH.sub.2 Br                                                                          H   OCF.sub.2 H                                                                             OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                      H  CH.sub.2 Br                                                                          H   CH.sub.3 OC.sub.2 H.sub.5                                         H  CH.sub.2 Br                                                                          H   CH.sub.3 CH.sub.2 OCH.sub.3                                       H  CH.sub.2 Br                                                                          H   OCH.sub.3                                                                               CH.sub.2 OCH.sub.3                                       H  CH.sub.2 Br                                                                          H   OCH.sub.3                                                                               C.sub.2 H.sub.5                                          H  CH.sub.2 Br                                                                          H   OC.sub.2 H.sub.5                                                                        OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   OCH.sub.2 CF.sub.3                                                                      OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CF.sub.3 OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CH.sub.2 F                                                                              OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CH.sub.2 Cl                                                                             OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   CH.sub.2 Br                                                                             OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   F        OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   I        OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   OCH.sub.2 CH.sub.2 F                                                                    OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   OCH.sub.2 CH.sub.2 CF.sub.3                                                             OCH.sub.3                                                H  CH.sub.2 Br                                                                          H   OCH.sub.2 CHF.sub.3                                                                     CH.sub.3                                                 H  CH.sub.2 Br                                                                          H   OCH.sub.2 CF.sub.3                                                                      CH.sub.3                                                 H  CH.sub.2 Br                                                                          H   Cl       OC.sub.2 H.sub.5                                         H  CH.sub.2 Br                                                                          H   OC.sub.2 H.sub.5                                                                        NHCH.sub.3                                               H  CH.sub.2 Br                                                                          H   OCH.sub.3                                                                               CH.sub.2 SCH.sub.3                                       H  CH.sub.2 Br                                                                          H   OCF.sub.2 H                                                                             CH.sub.3                                                 H  CH.sub.2 Br                                                                          H   Cl       OCF.sub.2 H                                              __________________________________________________________________________

                  TABLE 35                                                         ______________________________________                                          ##STR60##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 36                                                         ______________________________________                                          ##STR61##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub. 2 OCH.sub.3                              H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 37                                                         ______________________________________                                          ##STR62##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3 148-150                                H    CH.sub.2 F H      OCH.sub.3                                                                             OHC.sub.3 157-158                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3 )                          H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub. 3                                      H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub. 3                                                                            CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 38                                                         ______________________________________                                          ##STR63##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.3  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OHC.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 39                                                         ______________________________________                                          ##STR64##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 40                                                         ______________________________________                                          ##STR65##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3 169-172                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F H      CH.sub.3                                                                              Cl        174-178                                H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      Cl        142-148                                H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub. 3)                          H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F H      CH.sub.3                                                                              CH.sub.3  162-165                                H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              OC.sub. 2 H.sub.5                                                                     NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3 OCH.sub.3                              H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 41                                                         ______________________________________                                          ##STR66##                                                                     R.sup.1                                                                             R.sup.2    R.sup.3                                                                               X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3 131-133                                H    CH.sub.2 F H      OCH.sub.3                                                                             OCH.sub.3 145-148                                H    CH.sub.2 F H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF        H      CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2  H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2  H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                               CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2  CH.sub.3                                                                              CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F CH.sub. 3                                                                             OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F CH.sub.3                                                                              OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                               H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                               H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                               H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                              H      CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                              H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                              H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                       H      CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                       H      OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                       H      OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl      H      OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl      H      CH.sub.3                                                                              CH.sub.3                                         H    CHFCl      H      Cl     OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl      H      CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl      H      CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl      H      F      OCH.sub.3                                        H    CHFCl      H      OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl      H      OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl      H      C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F H      CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 42                                                         ______________________________________                                          ##STR67##                                                                     R.sup.1                                                                             R.sup.2   R.sup.3 X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             OCH.sub.3 168-171                                H    CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                      Cl        153-156                                H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F                                                                               H       CH.sub.3                                                                              CH.sub.3   94-96                                 H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2 H       CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2 H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2 H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub. 3                                                                              OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                             H       CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl     H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              CH.sub.3                                         H    CHFCl     H       Cl     OCH.sub.3                                        H    CHFCl     H       OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl     H       CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl     H       CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl     H       F      OCH.sub.3                                        H    CHFCl     H       OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl     H       OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl     H       C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 43                                                         ______________________________________                                          ##STR68##                                                                     R.sup.1                                                                             R.sup.2   R.sup.3 X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3 164-167                                H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             OCH.sub.3 145-149                                H    CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2 H       CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2 H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2 H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2 CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub. 2 F                                                                              CH.sub.3                                                                               OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                             H       CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl     H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              CH.sub.3                                         H    CHFCl     H       Cl     OCH.sub.3                                        H    CHFCl     H       OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl     H       CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl     H       CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl     H       F      OCH.sub.3                                        H    CHFCl     H       OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl     H       OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl     H       C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 44                                                         ______________________________________                                          ##STR69##                                                                     R.sup.1                                                                             R.sup.2   R.sup.3 X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3 167-172                                H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             OCH.sub.3 150-158                                H    CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F                                                                               H       CH.sub.3                                                                              CH.sub.3  182-184                                H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3 )                          H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2 H       CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2 H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2 H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                               OC.sub.2 H.sub.5                                                                      NHCH.sub. 3                                      H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                             H       CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl     H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              CH.sub.3                                         H    CH.sub.2 F                                                                               H       Cl     OCH.sub.3 181-183                                H    CHFCl     H       OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl     H       CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl     H       CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl     H       F      OCH.sub.3                                        H    CHFCl     H       OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl     H       OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl     H       C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3                                        ______________________________________                                    

                  TABLE 45                                                         ______________________________________                                          ##STR70##                                                                     R.sup.1                                                                             R.sup.2   R.sup.3 X      Y         mp (°C.)                        ______________________________________                                         H    CH.sub.2 F                                                                               H       CH.sub.3                                                                              OCH.sub.3 88-90                                  H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             OCH.sub.3 93-95                                  H    CH.sub.2 F                                                                               H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 F                                                                               H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Cl                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Cl                                                                              H       OCH.sub. 3                                                                            N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Cl                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 Br                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Br                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 Br                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHF.sub.2 H       CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHF.sub.2 H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHF.sub.2 H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 Cl                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 Br                                                                              CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               OCH.sub.3                                                                             OCH.sub.3                                        H    CHF.sub.2 CH.sub.3                                                                               CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 F                                                                               CH.sub.3                                                                               OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 F                                                                               CH.sub.3                                                                               OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCH.sub.3                                                                              H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCH.sub.3                                                                              H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHFCH.sub.3                                                                              H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHClCH.sub.3                                                                             H       CH.sub.3                                                                              OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHClCH.sub.3                                                                             H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CHClCH.sub.3                                                                             H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CH.sub.2 CH.sub.2 F                                                                      H       CH.sub.3                                                                              OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             OCH.sub.3                                        H    CH.sub.2 CH.sub.2 F                                                                      H       OC.sub.2 H.sub.5                                                                      NHCH.sub.3                                       H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(OCH.sub.3)(CH.sub.3)                           H    CH.sub.2 CH.sub.2 F                                                                      H       OCH.sub.3                                                                             N(CH.sub.3).sub.2                                H    CHFCl     H       OCH.sub.3                                                                             OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              OCH.sub.3                                        H    CHFCl     H       CH.sub.3                                                                              CH.sub.3                                         H    CHFCl     H       Cl     OCH.sub. 3                                       H    CHFCl     H       OCH.sub.3                                                                             CH.sub.2 OCH.sub.3                               H    CHFCl     H       CH.sub.3                                                                              OC.sub.2 H.sub.5                                 H    CHFCl     H       CH.sub.2 Cl                                                                           OCH.sub.3                                        H    CHFCl     H       F      OCH.sub.3                                        H    CHFCl     H       OCH.sub.3                                                                             CH(OCH.sub.3).sub.2                              H    CHFCl     H       OCHF.sub.2                                                                            OCH.sub.3                                        H    CHFCl     H       C.sub.2 H.sub.5                                                                       OCH.sub.3                                        5-F  CH.sub.2 F                                                                               H       CH.sub.2                                                                              OCH.sub.3                                        ______________________________________                                    

Test results indicate that the compounds of the present invention are highly active pre-emergent or post-emergent herbicides or plant growth regulants. Many of them have utility for broad-spectrum pre- and/or post-emergency weed control in areas where complete control of all vegetation is desired, such as around fuel storage tanks, ammunition depots, industrial storage areas, parking lots, drive-in theaters, around billboards, highway and railroad structures. Some of the compounds have utility for selective weed control in crops such as wheat and barley. Alternatively, the subject compounds are useful to modify plant growth.

The rates of application for the compounds of the present invention are determined by a number of factors, including their use as plant growth modifiers or as herbicides, the crop species involved, the types of weeds to be controlled, weather and climate, formulations selected, mode of application, amount of foliage present, etc.

In general tens, the subject compounds should be applied at levels of around 0.05 to 10 kg/ha, the lower rates being suggested for use on lighter soils and/or those having a low organic matter content, for plant growth modifications or for situations where only short-term persistence is required.

Formulations

Useful formulations of the compounds of formula(I) can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates and the like. Many of these may be applied directly.

Sprayable formulations can be extented in suitable media and used at spray volumes of from a few liters to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulation. The formulations, broadly, contain about 0.1% to 99% by weight of active ingredient(s) and at least one of (1) about 0.1% to 20% surfactant(s) and (2) about 1% to 99.9% solid or liquid inert diluent(s). More specially, they will contain these ingredients in the following approximate proportions:

    ______________________________________                                                     Weight Percent*                                                                  Active                                                           Formulations  Ingredient                                                                               Diluent(s)                                                                               Surfactant(s)                                ______________________________________                                         Wettable Powders                                                                             20-90      0-74     1-10                                         Oil Suspensions,                                                                              3-50     40-95     0-15                                         Emulsions, Solutions                                                           (including Emulsifiable                                                        concentrates)                                                                  Aqueous Suspension                                                                           10-50     40-84     1-20                                         Dusts          1-25     70-99     0-5                                          Granules and Pellets                                                                         0.1-95      5-99.9  0-15                                         High Strength 90-99      0-10     0-2                                          Compositions                                                                   ______________________________________                                          *Active ingredient plus at least one of a surfactant or a diluent equals       100 weight percent.                                                      

Lower or higher levels of active ingredient can, of course, be present depending on the intended use and the physical properties of the compound. Higher ratios of surfactants to activate ingredient are sometimes desirable, and are achieved by incorporation into the formation or by tank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books, Caldwell, N.J., but other solids, either mined or manufactured, may be used. The more absorptive diluents are preferred for wettable powders and the denser ones for dusts.

Typical liquid diluents and solvents are described in Marsden, "Solvent Guide", 2nd Ed., Interscience, New York, 1950. Solubility under 0.1% is preferred for suspension concentrates; Solution concentrates are preferably stable against phase separation at 0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC Publishing Corp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia of Surface Active Agents", Chemical Publishing Co., Inc., New York, 1964, list surfactants and recommended uses.

All formulations can contain minor amounts of additives to reduce foaming, caking, corrosion, microbiological growth, etc.

The methods of making such compositions are well known. Solutions are prepared by simply mixing the ingredients. Fine solid compositions are made by blending and, usually, grinding as in a hammer or fluid energy mill. Suspensions are prepared by wet milling (see, for example, Littler, U.S. Patent No. 3,060,084). Granules and pellets may be made by spraying the active material upon preformed granular carriers or by agglomeration techniques.

See J. E. Browning, "Agglomeration", Chemical Engineering, Dec. 4, 1967, pp, 147ff. and "Perry's chemical Engineer's Handbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57ff.

For further information regarding the an of formulation, see for example:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41; R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line 43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182; H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4; G. C. Klingman, "Weed Control as a Science", John Wiley and S. A. Evans, "Weed control Handbook", 5th Ed., Blackwell Scientific Publications, Oxford, 1968, pp. 101-103.

The compounds of the present invention can be used independently and may be used in combination with any other commercial herbicide. A summary of the possible combination herbicides is given below

    ______________________________________                                         Common Name                                                                    ______________________________________                                         acetochlor   acifluorfen   AC 252,214                                          AC 263,499   acrolein      alachlor                                            ametryn      amitrole      AMS                                                 asulam       assure        atrazine                                            BAS-514      barban        benefin                                             bensulfuron methyl                                                                          bensulide     bentazon                                            benzofluor   benzoylprop   bifenox                                             bromacil     bromoxynil    butachlor                                           buthidazole  butralin      butylate                                            cacodylic acid                                                                              CDAA          CDEC                                                CGA 82725    CH-83         chloramben                                          chlorbromuron                                                                               chlorimuron ethyl                                                                            chloroxuron                                         chlorpropham chlorsulfuron chlortoluron                                        cinmethylin  clethodim     clomazone                                           cloproxydim  clopyralid    CMA                                                 cyanzine     cycloate      cycluron                                            cyperquat    cyprazine     cyprazole                                           cypromid     dalapon       dazomet                                             DCPA         desmediphan   desmetryn                                           diallate     dicamba       dichlorbenil                                        dichlorprop  dichlofop     diethatyl                                           difenzoquat  dinitramine   dinoseb                                             diphenamid   dipropetryn   diquat                                              diuron       DNOC          DOWCO453ME                                          DPX-M6316    DSMA          endothall                                           EPTC         ethalfluralin ethoxfumesate                                       Express      fenac         fenoxaprop ethyl                                    fenuron      fenuron TCA   flamprop                                            fluazifop    fluazifop-butyl                                                                              fluazifop-P                                         fluchloralin fluometuron   fluorochloridone                                    fluorodifen  fluoroglycofen                                                                               fluridone                                           fomesafen    fosamine      glyphosate                                          haloxyfop    harmoney      hexaflurate                                         hexazinone   HW-52         imazamethabenz                                      imazapyr     imazaquin     imazethapyr                                         ioxynil      isopropalin   isoproturon                                         isouron      isoxaben      karbutilate                                         lactofen     lenacil       linuron                                             MAA          MAMA          MCPA                                                MCPB         mecoprop      mefluidide                                          methalpropalin                                                                              methabenzthiazuron                                                                           metham                                              methazole    methoxuron    metolachlor                                         metribuzin   metsulfuron methyl                                                                           MH                                                  molinate     monolinuron   monuron                                             monuron TCA  MSMA          My-93                                               napropamide  naproanilide  naptalam                                            neburon      nitralin      nitrofen                                            nitrofluorfen                                                                               norea         norfluazon                                          NTN-801      oryzalin      oxadiazon                                           oxyfluorfen  paraquat      pebulate                                            pendimethalin                                                                               perfluidone   phenmedipham                                        picloram     PPG-1013      pretilachlor                                        procyazine   profluralin   prometon                                            prometryn    pronamide     propachlor                                          propanil     propazine     propham                                             prosulfalin  prynachlor    pyrazon                                             pyrazolate   quizalofop ethyl                                                                             quizalofop                                          SC-2957      secbumeton    sethoxydim                                          siduron      simazine      SL-49                                               sulfometuron methyl                                                                         TCA           tebuthiuron                                         terbacil     terbuchlor    terbuthylazine                                      terbutol     terbutryn     thiameturon methyl                                  thiobencarb  triallate     triclopyr                                           tridiphane   trifluralin   trimeturon                                          2,4-D        2,4-DB        vernolate                                           X-52         xylachlor                                                         ______________________________________                                    

EXAMPLE 1 3-Bromo-4-fluoroacetylthiophene

3,4-Dibromothiophene(10 g, 0.041 mol)was dissolved in anhydrous ether and the solution was cooled to -78° C. under nitrogen atmosphere, and herein 17 ml of 2.5N n-butyl lithium was added dropwise.

The solution stirred for 10 min at -78° C. was cooled to -100° C., and herein ethyl fluoroacetate(4.8 ml, 0.05 mol) was added dropwise.

After stirring for 40 min, an excess of saturated solution of ammonium chloride was added and stirred.

The temperature of the reaction mixture was raised to room temperature, and herein an excess of ether was added to separate organic layer.

The organic layer was dried with magnesium sulfate, filtered and concentrated, and then the obtained residue was chromatographed through silica gel using 2:1 solution of methylene chloride/hexane to afford 6 g of the desired product. (white solid, yield:65%)

m.p.: 76°˜77° C.

¹ H NMR (CDCl₃) δ 5.40(d, 2H, J═48 Hz), 7.42(d, 1H, J═4 Hz), 8.37(d, 1H, J═4 Hz)

EXAMPLE 2 3-Bromo-4-(2-fluoromethyl- 1,3-dioxalan-2-yl)thiophene

3-Bromo-4-fluoracetylthiolphene(10 g, 0.045 mol) was added in ethylene glycol, and herein trimethyl silyl chloride (22.7 ml, 0.18 mol) was added under stirring.

After stirring for 12 hr, the solution was poured in an excess of saturated solution of sodium bicarbonate and stirred, and then an excess of ether was added and shaked to separate ether layer.

The ether layer was dried with magnesium sulfate, filtered and concentrated to afford 10.4 g of the desired product. (light brown liquid, yield: 87%)

¹ H NMR (CDCl₃) δ4.1 (m, 4H), 4.7 (d, 2H, J=48Hz), 7.4 (d, 1H, J═4 Hz), 7.6(d, 1H, J═4 Hz)

EXAMPLE 3 3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-4-thiophenesulfonamide

3-Bromo-4-(2-fluoromethyl- 1,3-dioxalan-2-yl)thiophene (19 g, 0.07 mol) was dissolved in anhydrous ether and the solution was cooled to -78° C. under nitrogen atmosphere, and herein n-butyl lithium (31 ml, 0.08 mol) was added dropwise.

After stirring for 10 min at -78° C., an excess of sulfur dioxide gas was added, and then the solution was stirred for 30 min at -78° C. The temperature of the reaction mixture was raised to room temperature, and the solution was filtered.

The obtained white solid was washed with ether, dried and dissolved in solution mixed 40 ml of water with 40 ml of isopropyl alcohol, and then the solution was cooled to 0° C.

After adding portion wise N-chlorosuccinimide (11.4 g, 0.085 mol), the solution was stirred for 2 hr at room temperature, and filtered to obtain a white solid.

The white solid was washed with water and dissolved in ethylacetate solution, and herein an excess of aqueous ammonia was added.

After stirring for 1 hr, the reacting solution was concentrated, and then the obtained solid was washed with a small quantity of ether to afford 13 g of the desired product (light yellow solid, yield: 68%).

m.p.: 126°˜30° C.

¹ H NMR (CDCl₃ +DMSO-d₆) δ 4.2(m, 4H), 4.86(d, 2H, J═48Hz), 6.6(brs, 2H), 7.85(d, 2H, J═4 Hz), 8.3(d, 2H, J═4 Hz)

IR(KBr): ν 3350, 3250 cm⁻¹

EXAMPLE 4 3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-methyltriazin-2- yl)aminocarbonyl]-4-thiophenesulfonamide

3-(2-fluoromethyl- 1,3-dioxalan-2-yl)-4-thiophenesulfonamide (1 g, 0.0037 mol) was dissolved in 20 ml of acetonitrile and phenyl (4-methoxy-6-methyltriazin-2-yl) carbamate (0.86 g, 0.0037 mol) was added at room temperature, and herein 0.8 ml of DBU was added dropwise.

After stirring for 1 hr, the reacting solution was diluted with 100 ml of methylene chloride, and was washed with hydrochloric acid solution.

The organic layer was dried with magnesium sulfate, filtered and concentrated. The obtained solid was washed with a small quantity of ether to afford 1.3 g of the desired product (yield: 84%).

m.p. :212°˜214° C.

¹ H NMR (DMSO-d₆) δ 2.51(s, 3H), 3.7-4.1(m, 4H), 4.05(s, 3H), 4.7(d, 2H, J═48Hz), 7.8(d, 2H, J═4 Hz), 8.5(d, 2H, J═4 Hz), 11.1(brs, 1H), 12.5(brs, 1H)

IR(KBr): ν (C=O) 1720 cm⁻¹

EXAMPLE 5 3-Bromo-2-fluoroacetylthiophene

2,3-dibromothiophene (10 g, 0.041 mol) was dissolved in anhydrous ether and cooled to -78° C. under nitrogen atmosphere, and herein 17 ml of 2.5N n-butyl lithium was added dropwise.

After stirring for 10 min at -78° C., the temperature of the reacting solution was cooled to -100° C., and herein ethylfluoro acetate(4.8 ml, 0.5 mol) was added dropwise.

After stirring for 40 min, an excess of saturated solution of ammonium chloride was added and stirred, and after raising the temperature to room temperature, an excess of ether was added to separate organic layer.

The obtained organic layer was dried with magnesium sulfate, filtered and concentrated. The residue was chromatographed through silica gel using 2:1 solution of methylene chloride and hexane to afford 6 g of the desired product (white solid, yield: 65%).

¹ H NMR (CDCl₃) δ 5.6(d, 2H, J═48 Hz), 7.25(d, 1H, J═5Hz), 7.75(d, 1H, J═5 Hz)

EXAMPLE 6 3-Bromo-2-(2-fluoromethyl- 1,3-dioxalan-2-yl)thiophene

3-Bromo-2-fluoroacetylthiophene (10 g, 0.045 mol) was dissolved in ethylene glycol, anti trimethylsilyl chloride (22.7 ml, 0.18 mol) was added under stirring.

After stirring for 12 hr, the solution was poured in an excess of saturated solution of sodium bicarbonate and stirred, and herein an excess of ether was added and stirred to separate ether layer.

The obtained ether layer was dried with magnesium sulfate, filtered and concentrated to afford 11 g of the desired product (light brown liquid, yield: 92%).

¹ H NMR (CDCl₃) δ4.1(m, 4H), 4.7(d, 2H, J═48 Hz), 6.95(d, 1H, J═5 Hz), 7.2(d, 1H, J═5 Hz)

EXAMPLE 7 2-(2-Fluoromethyl-1,3-dioxalan-2-yl)-3-thiophenesulfonamide

3-Bromo-2-(2-fluoromethyl-1,3-dioxalan-2-yl)thiophene (19 g, 0.07 mol) was dissolved in anhydrous ether anti the solution was cooled to -78° C., and herein n-butyl lithium (31 ml, 0.08 mol) was added dropwise under nitrogen atmosphere.

After stirring for 10 min at -78° C., an excess of sulfur dioxide gas was added, and after stirring 30 min at -78° C., the temperature of the reacting solution to filter the solid material.

The solid was dried and dissolved in solution mixed 40 ml of water with 40 ml of isopropyl alcohol, and after cooling to 0° C., herein N-chlorosuccinimide (11.4 g, 0.085 mol) was added portionwise.

After stirring for 2 hr at room temperature and filtering, the obtained solid was washed with water and dissolved in ethyl acetate solution, and herein an excess of aqueous ammonia was added while stirring for 1 hr at room temperature.

The reacted solution was concentrated, and then the obtained solid was washed with a small quantity of ether to afford 14 g of the desired product (yield: 74%).

m.p.: 120°˜121° C.

¹ H NMR (CDCl₃ +DMSO-d₆) δ 4.1(m, 4H), 4.75(d, 2H, J═48 Hz), 6.7(brs, 2H), 7.4(s, 2H)

IR(KBr): ν (NH₂) 3380, 3270 cm⁻¹

EXAMPLE 8 2-(2-Fluoro-methyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-methyltriazin-2-yl) aminocarbonyl]-3-thiophenesulfonamide

2-(2-fluoromethyl-1,3-dioxalan-2-yl)-3-thiophenesulfonamide (1 g, 0.0037 mol) was dissolved in 20 ml of acetonitrile and phenyl(4-methoxy-6-methyltriazin-2-yl) carbamate (0.86 g, 0.0037 mol) was added at room temperature, and herein 0.80 ml of DBU was added dropwise.

After stirring for 1hr, the solution was diluted with 100 ml of methylene chloride, and was washed with 5% hydrochloric acid solution.

The separated organic layer was dried with magnesium sulfate, filtered and concentrated, and then the obtained solid was washed with hexane or a small quantity of ether to afford 1.34 g of the desired product (yield: 87%).

m.p.: 186°˜189° C.

¹ H NMR (DMSO-d₆) δ 2.55(s, 3H), 4.0(m, 4H), 4.85(d, 2H, J═48 Hz), 7.6(q, 2H), 10.9(brs, 1H)

IR(KBr): ν (C=O) 1700 cm⁻¹

EXAMPLE 9 3-Fluoroacetylthiophene

3-Bromothiophene(10 g, 0.061 mol) was dissolved in anhydrous ether and the solution was cooled to -78° C. under nitrogen atmosphere, and herein 27 ml of 2.5N n-butyl lithium was added dropwise.

After stirring for 10 min at -78° C., the temperature of the solution was cooled to 100° C., and herein ethylfluoroacetate (7.1 ml, 0.074 mol) was added dropwise.

The solution was stirred for 40 min, and an excess of saturated solution of ammonium chloride was added.

After raising to room temperature, the reaction mixture was extracted with an excess of ether.

The obtained residue was dried with magnesium sulfate, filtered and concentrated, and then chromatographed through silica gel using 2:1 solution of methylenechloride/hexane to afford 6.4 g of the desired product (yield: 72%).

¹ H NMR (CDCl₃) δ 5.48(d, 2H, J═48 Hz), 7.35˜8.4 (m, 3H)

EXAMPLE 10 3-(2-Fluoromethyl- 1,3-dioxalan-2-yl)thiophene

3-Fluoroacetylthiophene (10 g, 0.069 mol) was dissolved in ethylene glycol, and herein trimethylsilyl chloride (35 ml, 0.275 mol) was added under stirring.

After stirring for 12 hr, the solution is poured in saturated solution of sodium bicarbonate and stirred.

The reaction mixture was extracted with an excess of ether, and then the obtained residue was dried with magnesium sulfate, filtered and concentrated to afford 11 g of the desired product(yield: 85%).

¹ H NMR (CDCl₃) δ 4.0(m, 4H), 4.44(d, 2H, J═48 Hz), 7.0-7.5(m, 3H)

EXAMPLE 11 3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-2-thiophenesulfonamide

3-(2-Fluoromethyl-1,3-dioxalan-2-yl)thiophene(5 g, 0.026 mol) was dissolved in anhydrous ether, and herein 12 ml of n-butyl lithium was added dropwise under nitrogen atmosphere.

After stirring for 1 hr at room temperature, the temperature of the solution was raised in order to reflux for 30 min, and the solution was cooled to -78° C. and sulfur dioxide gas was added.

The reacting solution was stirred for 30 min at -78° C., and the temperature was raised to room temperature. The obtained solid was filtered, dried and dissolved ill solution mixed 20 ml of water with 20 ml of isopropyl alcohol, and after cooling to 0° C., N-chlorosuccinimide (3.9 g, 0.029 mol) was added portionwise.

After stirring for 2 hr at room temperature, the obtained solid was filtered, washed with water and was dissolved in ethyl acetate, and herein an excess of aqueous ammonia was added.

After stirring for 1hr at room temperature, the reaction mixture was concentrated, and then the obtained solid was washed with a small quantity of ether to afford 2 g of the desired product (yield: 92%).

¹ H NMR (CDCl₃ +DMSO-d₆)δ 4.1(m, 4H), 4.65(d, 2H, J═48 Hz), 6.7(brs, 2H), 7.1 (d, 1H, J═5 Hz), 7.4(d, 1H, J═5 Hz)

EXAMPLE 12 3-(2-Fluoromethyl- 1,3-dioxalan-2-yl)-N-[(4-methoxy-6-methyltriazin-2- yl)aminocarbonyl]-2-thiophenesulfonamide

3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-2-thiophenesulfonamide (1 g, 0.0037 mol) was dissolved in 20 ml of acetonitrile and phenyl(4-methoxy-6-methyltriazin-2-yl)-carbamate (0.86 g, 0.0037 mol) was added at room temperature, and herein 0.8 ml of DBU was added dropwise.

After stirring for 1 hr, the solution was diluted with methylene chloride, and was washed with 5% hydrochloric acid solution. The separated organic layer was dried with magnesium sulfate filtered and concentrated, and then the obtained solid was washed with hexane and ether to afford 1.3 g of the desired product (yield: 84%).

mp.: 167°˜170° C.

¹ H NMR (DMSO-d₆) δ 2.55(s, 3H), 4.0(m, 4H), 4.7(d, 2H, J═48 Hz), 7.3(d, 1H, J═5 Hz), 7.8(d, 1H, J═5 Hz), 10.9(brs, 1H)

IR(KBr): ν (C=O) 1700 cm⁻¹

EXAMPLE 13 4-(1,1-Diethoxy-2-fluoroethyl)-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl-3-thiophenesulfonamide

4-(1,1-Diethoxy-2-fluoroethyl)-3-thiophenesulfonamide (1 g, 0.0034 mol) was dissolved in 20 ml of acetonitrile, and phenyl(4-methoxy-6-methylpyrimidin-2-yl) carbamate(0.87 g, 0.0034 mol) was added at room temperature, and herein 0.8 ml of DBU was added dropwise.

After stirring for 1 hr, the solution was diluted with 100 ml of methylene chloride, and washed with 5% hydrochloric acid solution. The residue was dried with magnesium sulfate, filtered and concentrated, and then the obtained solid was washed with hexane and ether to afford 1.2 g of the desired product.

m.p.: 145°˜148° C.

IR(KBr): ν (C=O) 1710cm⁻¹

EXAMPLE 14 3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl)-4-thiophenesulfonamide

3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-4-thiophenesulfonamide (1 g, 0.0037 mol) was dissolved in 20 ml of acetonitrile and phenyl (4-methoxy-6- methylpyrimidin-2-yl)carbamate (0.86 g, 0.0037 mol) was added at room temperature, and herein 0.8 ml of DBU was added dropwise.

After stirring for 1 hr, the solution was diluted with 100 ml of methylene chloride, and was washed with 5% hydrochloric acid solution. The separated organic layer was dried with magnesium sulfite, filtered and concentrated, and then the obtained solid was washed with hexane and ether to afford 1.3 g of the desired product (yield: 84%).

m.p.: 185°˜189° C.

IR(KBr): ν (C=O) 1709 cm⁻¹

EXAMPLE 15 Wettable Powder

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        80%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       sodium alkylnaphthalenesulfonate                                                                             2%                                               sodium ligninsulfonate        2%                                               synthetic amorphous silica    3%                                               kaolinite                     13%                                              ______________________________________                                    

The ingredients are blended, hammer-milled until all the solids are essentially under 50 microns, reblended, and packaged.

EXAMPLE 16 Wettable Powder

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        50%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       sodium alkylnaphthalenesulfonate                                                                             2%                                               low viscosity methyl cellulose                                                                               2%                                               diatomaceous earth            46%                                              ______________________________________                                    

The ingredients are blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in diameter. The product is reblended before packaging.

EXAMPLE 17 Granule

    ______________________________________                                         wettable powder of Example 16 5%                                               attapulgite granules (U.S.S. 20-40 mesh; 0.84˜0.42                                                     95%                                              ______________________________________                                    

A slurry of wettable powder containing 25% solids is sprayed on the surface of attapulgite granules in a double-cone blender.

The granules are dried and packaged.

EXAMPLE 18 Extruded Pellet

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        25%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                                                     10%                                              anhydrous sodium sulfate                                                       crude calcium lignisulfonate  5%                                               sodium alkylnaphthalenesulfonate                                                                             1%                                               calcium/magnesium bentonite   59%                                              ______________________________________                                    

The ingredients are blended, hammer-milled and then moistened with about 12% water. The mixture is extruded as cylinders about 3 mm diameter which are cut to produce pellets about 3 mm long. They may be used directly after drying, or the dried pellets may be crushed to pass a U.S.S. No. 20 sieve(0.84 mm openings). The granules held on a U.S.S. No. 40 sieve(0.42 mm openings) may be packaged for use and the fines recycled.

EXAMPLE 19 Oil Suspension

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        25%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       polyoxyethylene sorbitol hexaoleate                                                                          5%                                               highly aliphatic hydrocarbon oil                                                                             70%                                              ______________________________________                                    

The ingredients are ground together in sand mill until the solid particles have been reduced to under about 5 microns. The resulting thick suspension may be applied directly, but preferably after being extended with oils or emulsified in water.

EXAMPLE 20 Wetting Powder

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        20%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       sodium alkylnaphthalenesulfonate                                                                             4%                                               sodium ligninsulfonate        4%                                               low viscosity methyl cellulose                                                                               3%                                               attapulgite                   69%                                              ______________________________________                                    

The ingredients are thoroughly blended. After grinding in a hammer-mill to produce particles essentially all below 100 microns, the material is reblended and sifted through a U.S.S. No. 50 sieve(0.3 mm openings) and packaged.

EXAMPLE 21 Low Strength Granule

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        1%                                               methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       N,N-dimethylformamide         9%                                               attapulgite granule (U.S.S. 20-40 sieve)                                                                     90%                                              ______________________________________                                    

The active ingredient is dissolved in the solvent and the solution is sprayed upon dedusted granules in a double cone blender.

After spraying of the solution has been completed, the blender is allowed to run for a short period and then the granules are packaged.

EXAMPLE 22 Aqueous Suspension

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                       40%                                               methyltriazin-2-yl)aminocarbonyl]-4-                                           thiophenesulfonamide                                                           polyacrylic acid thickener   0.3%                                              dodecylphenol polyethylen glycol ether                                                                      0.5%                                              disodium phosphate           1%                                                monosodium phosphate         0.5%                                              polyvinyl alcohol            1%                                                water                        56.7%                                             ______________________________________                                    

The ingredients are blended and ground together in a sand mill to produce particles essentially all under 5 microns in size.

EXAMPLE 23 Solution

    ______________________________________                                         ammonium salt of N-[(4,6-dimethoxytriazin-2-yl)amino-                                                       5%                                                carbonyl]-3-(2-fluoromethyl-1,3-dioxalan-2-yl)-4-                              thiophensulfonamide                                                            water                        95%                                               ______________________________________                                    

The salt is added directly to the water with stirring to produce the solution, which may then be packaged for use.

EXAMPLE 24 Low Strength Granule

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                       0.1%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophene-                                 sulfonamide                                                                    attapulgite granules (U.S.S. No. 20-40 mesh)                                                                99.9%                                             ______________________________________                                    

The active ingredient is dissolved in a solvent and the solution is sprayed upon dedusted granules in a double-cone blender. After spraying of the solution has been completed, the material is warmed to evaporate the solvent. The material is allowed to cool and packaged.

EXAMPLE 25 Wettable Powder

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        40%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       dioctyl sodium sulfosuccinate 1.5%                                             sodium ligninsulfonate        3%                                               low viscosity methyl cellulose                                                                               1.5%                                             attapulgite                   54%                                              ______________________________________                                    

The ingredient are throughly blended, passed through an air mill, to produce an average particle size under 15 microns, reblended, and sifted through a U.S.S. No. 50 sieve(0.3 mm opening) before packaging. All compounds of the invention may be formulated in the same manner.

EXAMPLE 26 Granule

    ______________________________________                                         wettable powder of Example 25                                                                        15%                                                      gypsum                69%                                                      potassium sulfate     16%                                                      ______________________________________                                    

The ingredients are blended in rotating mixer and water sprayed on to accomplish granulation. When most of the material has reached the desired range of 1.0 to 0.42 cm (U.S.S. #18 to 40 sieves), the granules are removed, dried, and screened. Oversized material is crushed additional material in the desired range. These granules contain % active ingredient.

EXAMPLE 27 High Strength Concentrate

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        99%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       silica aerogel                0.5%                                             synthetic amorphous silica    0.5%                                             ______________________________________                                    

The ingredient are blended and ground in a hammer-mill to produce a material essentially all passing a U.S.S. No. 50 screen (0.3 mm opening). The concentrate may be formulated further if necessary.

EXAMPLE 28 Wettable Powder

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        90%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       dioctyl sodium sulfosuccinate 0.1%                                             synthetic fine silica         9.9%                                             ______________________________________                                    

The ingredient are blended and ground in a hammer-mill to produce particles essentially all below 100 microns. The material is sifted through a U.S.S. No. 50 screen and the packaged.

EXAMPLE 29 Wettable Powder

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        40%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       sodium ligninsulfonate        20%                                              montmorillonite clay          40%                                              ______________________________________                                    

The ingredients are throughly blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in size. The material is reblended and the packaged.

EXAMPLE 30 Oil Suspension

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        35%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       blended of polyalcohol carboxylic ester and oil soluble                                                      6%                                               petroleum sulfonate                                                            xylene                        59%                                              ______________________________________                                    

The ingredients are combined and ground together in a sand mill to produce particle essentially all below 5 microns. The product can be used directly, extended with oil, or emulsified in water.

EXAMPLE 31 Dust

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        10%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       attapulgite                   10%                                              pyrophyllite                  80%                                              ______________________________________                                    

The active ingredient is blended with attapulgite and then passed through a hammer-mill to produce particles substantially all below 200 microns. The ground concentrate is then blended with powdered pyrophyllite until homogeneous.

EXAMPLE 32 Emulsifiable Concentrate

    ______________________________________                                         3-(2-Fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-                                                        10%                                              methyltriazin-2-yl)aminocarbonyl]-4-thiophenesulfonamide                       chlorobenzene                 84%                                              sorbitan monostearate and polyoxyethylene condensates                                                        6%                                               thereof                                                                        ______________________________________                                    

The ingredients are combined and stirred to produce a solution which can be emulsified in water for application.

EXAMPLE 33 Pre-emergence test

To produce a suitable preparation of active compound, 1 pan by weight of active compound is mixed with 5 parts by weight of acetone, 1 pan by weight of alkylaryl polyglycol ether of emulsifier is added and the concentrate is diluted with water to the desired concentration

Seeds of the test plants are shown in normal soil and, after 24 hours, watered with the preparation of the active compound.

It is expedient to keep constant the amount of water per unit area. The concentration of the active compound in the preparation is of no importance, only the amount of active compound applied per unit area being desicive.

After three weeks, the degree of damage to the plants is rated in % damage in comparison to the development of the untreated control.

The figures denote:

0%=no action (like untreated control)

20% =slight effect

70% =herbicidal effect

100% =total destruction.

In this test, the active compounds(I) according to the preparation Examples exhibit a better herbicidal activity against nomo- and dicotyledon weeds.

EXAMPLE 34 Post-emergence test

To produce a suitable preparation of active compound, 1 part by weight of active compound is mixed with 5 parts by weight of acetone, 1 part by weight of alkylaryl polyglycol ether of emulsifier is added and the concentrate is diluted with water to the desired concentration.

Test plants which have a height of 5˜15 cm are sprayed with the preparation of the active compound in such a way as to apply the particular amounts of active compound desired per unit area. The concentration of the spray liquor is so chosen that the particular amounts of active compound desired are applied in 2,000 l of water/ha. After three weeks, the degree of damage to the plants is rated in % damage in comparasion to the development of the untreated control.

The figures denote:

0%=no action (like untreated control)

20%=slight effect

70%=herbicidal effect

100% =total destruction.

In this test, the active compounds(I) according to the preparation Examples exhibit a better herbicidal activity against mono- and dicotyledon weeds.

It is understood that the specification and examples are illustrative but not limitative of the present invention and that other embodiments within the spirit and scope of the invention will suggest themselves to those skilled in the art.

The herbicidal proficiency of the active ingredients of the present invention is evident from the test results which are recorded in following Tables.

The following Tables are represented pre- and post-emergence herbicidal evaluation of following "test compounds".

    __________________________________________________________________________     Structure               X   Y   Z  Comp. No.                                   __________________________________________________________________________      ##STR71##                                                                                              ##STR72##                                                                          ##STR73##                                          ##STR74##                                                                                              ##STR75##                                              ##STR76##                                                                                              ##STR77##                                                                          ##STR78##                                                                          ##STR79##                                                                         ##STR80##                                   ##STR81##                                                                                              ##STR82##                                                                          ##STR83##                                                                          ##STR84##                                                                         ##STR85##                                   ##STR86##                                                                                              ##STR87##                                                                          ##STR88##                                                                          ##STR89##                                                                         ##STR90##                                   ##STR91##                                                                                              ##STR92##                                                                          ##STR93##                                                                          ##STR94##                                      ##STR95##                                                                      ##STR96##                                                                                              ##STR97##                                                                          ##STR98##                                                                          ##STR99##                                                                         ##STR100##                                  ##STR101##                                                                                             ##STR102##                                                                         ##STR103##                                                                         ##STR104##                                                                        ##STR105##                                  ##STR106##                                                                                             ##STR107##                                                                         ##STR108##                                                                         ##STR109##                                                                        ##STR110##                                  ##STR111##                                                                                             ##STR112##                                                                         ##STR113##                                                                         ##STR114##                                                                        ##STR115##                                  ##STR116##                                                                                             ##STR117##                                                                         ##STR118##                                                                         ##STR119##                                                                        ##STR120##                                  ##STR121##                                                                                             ##STR122##                                                                         ##STR123##                                                                         ##STR124##                                                                        ##STR125##                                  ##STR126##                                                                                             ##STR127##                                                                         ##STR128##                                                                         ##STR129##                                                                        ##STR130##                                  ##STR131##                                                                                             ##STR132##                                                                         ##STR133##                                                                         ##STR134##                                                                        ##STR135##                                  ##STR136##                                                                                             ##STR137##                                                                         ##STR138##                                                                         ##STR139##                                                                        ##STR140##                                  ##STR141##                                                                                             ##STR142##                                                                         ##STR143##                                                                         ##STR144##                                                                        ##STR145##                                 __________________________________________________________________________

    __________________________________________________________________________     PLANT RESPONSE SCREENING (Herbicide)                                                                BROJA                                                     Comp.                (SETVI)                                                   No. TYPE                                                                               kg/ha                                                                              SORBI                                                                              ECHOR                                                                               [AGRSM]                                                                              DIGSA                                                                               PANDI                                                                               SOLNI                                                                               AESIN                                                                               ABUTH                                                                               XANSI                                                                               CAGHE                 __________________________________________________________________________      1  PRE .05  90  90   90    70   90   20   40   65   80  100                       POST                                                                               .05  70  90  100    20   0    0    60   25   70  100                    2  PRE .05 100 100  100    90  100   20   40   50   90  100                       POST                                                                               .05  90 100  100    40   10        90  100   60   60                    3  PRE .05  65  30   40    15   10   20   0    50        25                       POST                                                                               .05  10  20   30    20   0    0    0    0    0    0                    20  PRE .1  100 100  100    60   65   90   40   90   90  100                       POST                                                                               .1   80 100   90    50   30   75   90  100  100   90                   21  PRE .05  40  60   0     10   0    0    0    10        0                        POST                                                                               .05  50  60   30    0    0    0    0    0    0    0                    22  PRE .05  15  0    0     30   0    20   10   10   60   0                        POST                                                                               .05  20  20   0     20   0    0    0    0    0    0                    25  PRE .05 100 100  100   100  100   80   90   90   90  100                       POST                                                                               .05 100 100  100   100   90   80   90  100  100  100                   26  PRE .05 100 100  100   100  100   60  100   90  100  100                       POST                                                                               .05 100 100  100   100   90   50   90  100  100  100                   27  PRE .05 100 100  100   100  100    60  80   90   90   60                       POST                                                                               .05  90 100   80   100  100   50  100  100  100  100                   28  PRE .05  90 100   80    90  100   90   60   40   80   30                       POST                                                                               .05  30 100  100    70        80   90   70  100  100                   29  PRE .05 100 100   90   100   90   60  100  100   90  100                       POST                                                                               .05 100 100  100   100   90   60  100  100  100  100                   30  PRE .05  90 100   80   100   90   50  100  100   95  100                       POST                                                                               .05 100 100  100   100   60   70  100  100  100  100                   40  PRE .05  60  40   60    50   70   0    0    0    0    20                       POST                                                                               .05  50  30   80    10        40   0    0    40   0                    41  PRE .05  30  80   80    30        20   0    0    60   80                       POST                                                                               .05   30                                                                                60   50    0         30   20   0    70   0                    42  PRE .05  40  10   60    0    40   0    0    0    0    35                       POST                                                                               .05  20  0    20    0         60   0    0   100   20                   43  PRE .05  50  60         20   70   20   0    20   0    20                       POST                                                                               .05  70  60   0     0         30   0    0    30   60                   44  PRE .05  0   0    0     0    0    20   0    0    30   30                       POST                                                                               .05  60  0    80    0         0    20   0    90   50                   45  PRE .05 100 100  100   100  100   30   90   90   75  100                       POST                                                                               .05 100 100  100   100  100   60  100  100  100  100                   46  PRE .05 100  90  100    60  100   20   50   65  100  100                       POST                                                                               .05  90 100  100    50  100   0    80   50  100   30                   47  PRE .05  20  70   0     0    0    70   0    0    0    0                        POST                                                                               .05  40  35   0     0    0    70   15   0    30   0                    48  PRE .05 100  60   0     40        0    20   20   0    20                       POST                                                                               .05 100  90   80    0    0    0    40   0    65   40                   49  PRE .05  70  70   40    50        0    20   20   0    0                        POST                                                                               .05 100  70  100    20   0    0    50   0    70   30                   50  PRE .06 100 100   90   100  100   50   70   20   80  100                       POST                                                                               .05 100 100   90    80   90   50   90   70       100                   51  PRE .06 100 100   85    90  100   20   70   65   80  100                       POST                                                                               .05 100 100  100   100  100   30  100   90       100                   52  PRE .06  90  90   60    70   85   25   60   70   70   60                       POST                                                                               .05  90 100   90    60   70   50   90   60        70                   53  PRE .06  20  30   0     20   20   0    0    0    0    60                       POST                                                                               .05  60  25   20    20   40   20   30   0         0                    54  PRE .06  90  90   40    90   50   20   90   80   90  100                       POST                                                                               .05 100  90   90    90   40   40  100   90        90                   55  PRE .06  90  80   60    80   90   20   80   80   90  100                       POST                                                                               .05 100  90   80    70   65   40  100   90        90                   56  PRE .05  90  30         25   65   0    0    0    0    30                       POST                                                                               .05  70  60   90    35   90   0    50   15  100   85                   57  PRE .05  90  90   70    90   85   20   0    20   70   80                       POST                                                                               .05  70 100   60    25  100   30   65   10  100   20                   58  PRE .05  25  60   20    35   65   50   0    0    0    0                        POST                                                                               .05  70  70   50    30   65   25   30   0    25   30                   59  PRE .05  80  25   30    35   50   0    35   20   75   90                       POST                                                                               .05 100  80   30    50   90   25  100   60   70   65                   60  PRE .05  35  0    0     0    0    0    20   0    60   60                       POST                                                                               .05  80  60   25    20   30   20   65   50   30   65                   61  PRE .1   65  20   70    0    70   0    0    0         80                       POST                                                                               .1   70  55   80    0    0    20   0    0    0    80                   62  PRE .1  100 100  100   100  100   50   90   90   90  100                       POST                                                                               .1  100 100  100    70  100   25   70   25  100  100                   63  PRE .05  50  20   0     0    20   0    0    0    50   90                       POST                                                                               .05  60  50   20    40   40   20   0    0    10  100                   64  PRE .1  100  80  100    70   70   60   50   90        95                       POST                                                                               .1   90  80   90    40   20   0    80   90  100  100                   65  PRE .1  100  90   90    65   65   60   80    80  90  100                       POST                                                                               .1  100  90   70    30   10   0    80   50   20   80                   66  PRE .1  100  80   60    40   30   20   40   70   60   60                       POST                                                                               .1   90  80   60    10   20   20   70   30   85   70                   68  PRE .1  100 100  100    90  100   20   15   40       100                       POST                                                                               .1   80  90   90    80   95   30   20   30   90  100                   76  PRE .05 100 100  100   100  100   60   0    0    10   20                       POST                                                                               .05  90  65   95    65  100   40   0    0    0    50                   77  PRE .05 100 100  100   100  100   20   0    30   90   60                       POST                                                                               .05  80 100  100   100  100   30  100   30  100  100                   78  PRE .05 100  80   10    60        20   0     0   0    50                       POST                                                                               .05  90  80   50    20  100   0    50   0    55   50                   79  PRE .05  60  70   10    50  100   0    0    0    0    0                        POST                                                                               .05  70  70   0     20        20   60   0    40   60                   80  PRE .05 100 100  100    90  100   90   10   50   50  100                       POST                                                                               .05  90 100  100    80  100   50   60   50  100  100                   81  PRE .05 100 100  100   100  100   90   90   90   90  100                       POST                                                                               .05 100 100  100   100  100   90  100   60  100  100                   82  PRE .05 100 100   70   100  100   30   60   60   80  100                       POST                                                                               .05  90 100   90    90  100   0   100   60  100  100                   83  PRE .05  60 100  100    20   80   60   0    0    0    90                       POST                                                                               .05   60                                                                                90   0     0   100   40   30   0    40   60                   84  PRE .05  40 100   70    60  100   20   0    0    50   65                       POST                                                                               .05  80 100   70    30  100   30   60   20   70   90                   85  PRE .05  10 100   20    30   80   70   0    0    0    60                       POST                                                                               .05  30  70   0     20   0    40   40   0    20   40                   86  PRE .05 100 100  100   100  100   80   90   90  100  100                       POST                                                                               .05 100 100  100   100  100  100  100  100  100  100                   87  PRE .05  90  70   70    40        30   0    20   20  100                       POST                                                                               .05  30  45   80    20        20   20   0    60   20                   88  PRE .05  65 100   60    90  100   0    0    0    20   55                       POST                                                                               .05  50  70  100    20  100   20   0    0    60   50                   89  PRE .05  30  40   30    30        0    0    0    20   0                        POST                                                                               .05  0   0    20    0         30   0    0    0    50                   __________________________________________________________________________

      PLANT RESPONSE SCREENING (Herbicide) UPLAND WEED SPECIES  SETVI POLHY      PADDY WEED SPECIES Comp. No. TYPE kg/ha LYPES TRZAW GLXMX ZEAMX DACGL      AMAVI (SETVI) RUMJA (COMCO) AESIN CAGHE ORYSA ECHOR CYPDI ANEKE         4 PRE .1  90 100 100 100  90 100 (100)  85 100 100 100 100 100 100      60  POST .1  60  80 100  90 100 100 (100) 100 100 100 100 100 100 100      65  5 PRE .1 100  60  90 100  90 100  (80)  90 100 100  90 100  95 100      50  POST .1  90  35  85  90 100 100  (60)  90  85 100 100  90  90 100      10  6 PRE .1  90 100  90 100 100 100 (100)  90 100  90 100 100  90 100      20  POST .1  90  70 100  90 100 100  (70)  90  80 100 100  90 100  90      10  7 PRE .1  90  50 100 100 100 100 (100)  90 100 100 100 100 100 100      90  POST .1  70  45 100 100 100 100 (100) 100 100 100 100 100 100 100      70  8 PRE .1  90  60 100 100  90 100 (100)  90 100 100 100 100 100 100      80  POST .1 100  25 100 100 100 100 (100) 100 100 100 100  90 100 100      70  9 PRE .1  15  0  0  0  20  20  (25)  10   0  0  60  90  60  0  POST      .1  30  10  15  0  60  60  (25)  30  90  0  25  60  10  30  0 10 PRE .1      30  65  15  90  70  90  (90)  70  95 100  90  90  90 100  20  POST .1      40  70  90  60  90 100  (90) 100 100  40 100  65  70 100  0 11 PRE .1      60  40  10  30  70  90  (90)  80  95  15  95  70  60   0  POST .1  10      10  80  30  90 100  (40)  65  80  10 100  60  60  80  0 12 PRE .1  70      10  65  20  65 100  (95)  40  95  65  95 100  80 100  80  POST .1  80      20 100  35  75 100  (60)  70 100 100 100  65  75 100  10 13 PRE .1  60      0  0  0  30   (0)  10   20  50  90  80 100  90  POST .1   20  10  45  0      50  70  (10)  20  90   20  35  25  60  0 14 PRE .1  50  0  0  0  0  0      (0)  0   20  15  0  0  0  0  POST .1  15  0  0  0  0  15  (0)  15  50  0       0  10  10   0 15 PRE .1  50  0  0  0   40  (25)  0  60  20  0  70  0      0  POST .1  20  0  0  0  15  40  (20)  0  0  0  0  10  0  70  0 16 PRE      .1  90  15 100 100  70  90  (70)  85  95  80  80  90  80  90  50  POST      .1  65  10  90  90  70  90  (60)  90 100 100 100  60 100  60  0 17 PRE      .1  70  0  70  70  90 100  (60)  80  95  65  60  40  50 100  10  POST .1       50  10  90  30  20  80  (20)  70 100  90  85  35  30  60  0 18 PRE .1      95  10 100  90  65  90  (90)  95 100  65  60  80  40   0  POST .1  70      10  90  65  35 100  (40)  70  80 100 100  20  65 100  10 19 PRE .1  90      90 100 100  80  90 (100)  70 100  90  95 100 100 100  70  POST .1  70      40 100  90 100 100  (80)  80 100  90 100 100 100  95  0 23 PRE .1 100      10 100 100  80  90 (100)  75 100 100  90 100 100  90  90  POST .1  30  0      100 100 100 100  (70) 100 100 100 100  70 100  65  30 24 PRE .1 100  0      100 100  80  90 (100)  75 100 100 100 100  95 100  70  POST .1  85  0      100 100  70 100  (60)  90 100 100 100  80  90 100  30 31 PRE .1  90  90      70 100  80  90 (100)  80 100  70  90 100  90 100  60  POST .1  70  80      90 100 100 100 (100) 100 100  90 100  70 100 100  40 32 PRE .1  70  25      20 100  70 100 (100)  60 100  25  40  60  60 100  0  POST .1  70  35  70       90  75  80  (70)  60  90  65  30  65  70 100   0 33 PRE .1  30  20  30      90  70  90 (100)  70  90  25  90 100 100 100  60  POST .1 100  60 100      100 100 100 (100) 100 100 100 100  90 100 100  0 34 PRE .1  70  40  10      20  70 100 (100)  50  90  10  60 100 100 100  60  POST .1 100  40  70      90 100 100 (100) 100  90  90  30 100 100 100  30 35 PRE .1  70  10  20      10  20  90  (90)  40  80  0  10  90  70 100  0  POST .1 100  10  60  60      80  70  (60)  40  60  10  20  85  80 100  0 36 PRE .1  30  0  10  0  0      0  (0)  0  60  0  0  60  0 100  15  POST .1  65  0  55  0  15  50  (55)      60  50  30  0  60  0 100  0 37 PRE .1 100  10 100 100  70  90 (100)  70      100 100 100  80  90  70  90  POST .1 100  25 100 100 100 100 (100)  90      100 100 100  90 100 100  30 38 PRE .1 100  10 100  65  60  90 (100)  70      90  90  60  90  25 100  60  POST .1 100  10 100 100 100 100 (100) 100      100 100 100  30  70 100  0 39 PRE .1 100  20  90  90  10  90 (100)  70      90  70  60  90  60  0  0  POST .1 100  20 100 100  70 100 (100)  90 100      100 100  35  80 100  0 67 PRE .1  30  0  0  0  60  70  (65)  0  20  0      40  80  60  70  0  POST .1  40  35  30  0  70 100  (40)  20   10  80  70       65  80  0 69 PRE .1  10  20  20  85  70  90  (65)  10  80  0  80 100      90 100  0  POST .1  40  15  80  65  80  70  (40)  70  90  50 100  60  80       70  0 70 PRE .1  55  0  0  0  20  40  (60)  0  0  0  0  20  20 100  0      POST .1  65  10   0  55  60  (0)  10   50  40  20  0  0  0 71 PRE .1  90       0  70  90  80  90  (80)  20  90  30  80 100  40 100  10  POST .1  70      20  85 100 100 100  (60)  70   70  70  70  70  80  0 72 PRE .1  70  10      60  40  30  90  (65)  25  90  20  55  25  0  0  0  POST .1  70  10  90      20  60  70  (60)  60   65  65  55  0  50  40 73 PRE .1  80  90  30 100      70  90 (100)  65  90  20  90 100  90 100  0  POST .1 100  70  60 100 100      100 (100)  70  90  65 100  90 100 100  15 74 PRE .1 100  10  25 100  70      100 (100)  70  90  20  90 100  65 100  40  POST .1 100  20  90 100 100      100 (100)  90 100  90 100 100 100 100  20 75 PRE .1  90  10  15  70  50      90 (100)  70  90  20  65  90  70  90  0  POST .1 100  10  85 100  65 100      (100)  90 100  65  65  60  90 100       10

      PRIMARY SCREENING (Herbicide)           BROJA                  (SETVI)      Comp. No. TYPE kg/ha ZEAMX GLXMX GOSHI TRZAW ORYSA SORBI ECHOR [AGRSM]      DIGSA PANDI SOLNI AESIN ABUTH XANSI CAGHE         2 PRE .1  80  70  60  50 100  70  80  70  90 100  60  70  90  80 100       .05  70  65  50  30 100  80  90  90  80  90  50  70  80  80 100   .025      50  50  20  10  80  70  60  90  65  80  40  30  65  70  90   .012  10      40  10  0  60  45  50  65  10  65  40  20  50  40 100   .006  0  20  0      0  20  10  0  50  0  30  20  10  10  10  70  POST .1  70 100  50  60 100       90  90  80  30 100  20 100 100 100 100   .05  70 100  30  30  80  80      65  70  20 100  20 100  90 100 100   .025  20 100  20  20  50  70  50      65  10  20  20 100  40 100 100   .012  10 100  20  10  30  70  40  50      10  20  10  80  30   40   .006  0 100  0  0  30  30  10  40  0  0  0  65       20  70  0 20 PRE 1  70  60 100  30 100 100 100  70  80  90  90  40  90      90 100   .05  40  50  60  0 100  90 100  60  70  90  90  30  70  90 100       .025  20  45   0  70  70  70  30  40  30  70  10  60  70  50   .012  0      20  40  0  50  30  50   0  20  0  50  0  0  60  0   .006  0  0  40  0      40  20  30   0  0  0  30  0  0  0  0  POST .1  60  80  50  10  65 100      95  100  50 100  75 100 100 100 100   .05  20  80  30  10  60 100   90      100  40 100  70 100 100 100 100   .025  10  60  20  10  50 100  90  90      40 100  65  80  65  95 100   .012  0  50  10  0  50  90  65  80  10  90      50  60  20  65 100   .006  0  40  0  0  10  70  40  50  0  60  50  40      20  30  30 25 PRE .1 100  80  90  60 100 100  90  90 100 100  90  65  90       90 100   .05 100  70  90  50 100 100  90  70 100 100  90  60  90  90      100   .025  90  50  70  35 100  90  70  70 100 100  70  40  80  70  50      .012  50  30  50  0  70  90  60  70  70 100  60  30  60   50   .006  50      0  40  0  50  60  30  70  40  80  50  0  20  20  20  POST .1 100 100  60       95 100 100  80  100 100 100  85 100 100 100 100   .05  95 100  50  90      100 100  85  100 100 100  80 100 100 100 100   .025  90  70  40  65 100      100  65  100  90 100  70 100  85  90 100   .012  65  65  30  30  95  90      60  100  60 100  50  90  70  65  60   .006  10  50  10  20  95  80  60      95  30 100  50  65  50  40  50 26 PRE 1 100 100 100 100 100 100 100  100      100 100  90 100 100 100 100   .05 100 100 100 100 100 100 100  100 100      100  70  80 100 100 100   .025 100  80 100  90 100 100 100  100 100 100      60  70 100 100 100   .012 100  70 100  80 100 100 100  100 100 100  50      40  90  80 100   .006  90  60  60  60 100  80  90  90  90  90  20  0  80       80 100  POST .1 100 100  65 100 100 100 100  100 100 100  70 100 100      100 100   .05 100 100  65 100 100 100 100  100 100 100  60 100  90 100      100   .025 100 100  60 100 100 100 100  100  90 100  50 100  90 100 100       .012 100  80  50  65 100 100 100  70  90 100  50  90  70 100 100   .006      100  50  50  50 100 100  95  70  60 100  30  80  40  65  60 27 PRE .1      100 100 100  90 100 100  90 (100) 100 100  70  60 100 100 100   .025 100       70  40  20 100  50  50  (65) 100 100  30  40  65  40  40   .00625  60      30  0  0  90  30  30  (30)  80 100  0  0  0  0  0   .00156  0  0  0  0      30  0  0  (0)  40  90  0  0  0  0  0  POST .1 100 100 100  70 100 100      100 (100) 100 100  50 100 100 100 100   .025  70 100  50  50 100 100  65      (100) 100 100  50 100 100 100 100   .00625  40 100  0  0  90  80  40      (20)  20 100  0  70  50  40  0   .00156  0  40  0  0  40  30  0  (0)  0      60  0  40  0  0  0 28 PRE 1 100  80  90  40 100  90 100  (30) 100 100      100  60  80 100 100   .025  50  30  20  0 100  30  60  (0)  40 100  60      0  40  40 100   .00625  0  0  0  0  80  0  0  (0)  0 100  0  0  0  0  0       .00156  0  0  0  0  40  0  0  (0)  0  40  0  0  0  0  0  POST .1  80      100  50  40  90 100 100  (65)  40 100 100 100 100 100  65   .025  70  50       0  0  90 100 100  (20)  0  50  90  65 100  80  30   .00625  20  30  0      0  70  30  30  (0)  0  10  0  20  70  60  0   .00156  0  0  0  0  20  0      0  (0)  0  0  0  0  65  0  0 29 PRE .1 100 100 100  50 100 100 100  100      100 100  90 100 100 100 100   .05 100 100 100  10 100 100 100  100 100      90  80  90 100 100 100   .025 100 100  90  0 100 100 100  100 100  80      60  90 100 100 100   .012 100 100  90  0 100 100 100  80 100  70  50  90       90 100 100   .006 100  90  80  0  90 100  80  65  90  50  0  50  70  90      100  POST .1 100 100 100  90 100 100 100  100 100 100  70 100 100 100      100   .05 100 100  60  50 100 100 100  100 100 100  65 100 100 100 100      .025 100 100  50  60 100 100 100  100  90 100  60 100 100 100 100   .012      100 100  30  25 100 100 100  100  90  90  50 100  90 100 100   .006 100      100  0  0 100 100  80  65  20  65  30 100  70 100  65 30 PRE 1 100  90      90  0 100 100  90  70 100  90  70  80  80  90  70   .05 100  90  90  0      100  90  80  60 100  90  70  70  80  90  60   .025 100  90  90  0 100      90  70  60 100  90  70  70  70  90  50   .012  90  90  90  0 100  80  50       30  90  90  60  50  50  90  40   .006  40  70  90  0  60  60  30  20      40  50  60  30  30  70  40  POST .1 100 100  50  40 100 100 100  100 100      100  60 100 100 100 100   .05 100 100  40  40 100 100  80  100 100 100      60 100 100 100 100   .025 100 100  10  10 100 100  60  100 100 100  50      100 100  10 100   .012  90 100  0  10  50 100  60  100  90 100  50 100      90 100 100   .006  80  90  0   0  30  90  50  70  70  95  40 100  65  85       60 40 PRE .1  10  0  0  30 100 100  60  (40) 100 100  50  0  0  40  40       .05  0  0  0  0  90  80  20  (0)  60  60  40  0  0  20  10   .025  0  0       0  0  60  10  0  (0)  40  40  0  0  0  0  0   .0125  0  0  0  0  30  0      0  (0)  30  30  0  0  0  0  0   .006  0  0  0  0  0  0  0  (0)  0  0  0      0  0  0  0  POST .1  0  0  0  50  50  60  30  (40)  30  40  0  0  0  50      40   .05  0  0  0  30  40  50  0  (20)  10  20  0  0  0  0  0   .025  0      0  0  0  0  0  0  (0)  0  0  0  0  0  0  0   .0125  0  0  0  0  0  0  0      (0)  0  0  0  0  0  0  0   .006  0  0  0  0  0  0  0  (0)  0  0  0  0  0       0  0 41 PRE 1 100  20  40  50 100  90  60  (50)  50  70  70  20  0  80      100   .05  50  0  0  20  70  40  40  (40)  20   40  40  0  0  70  60      .025  20  0  0  0  50  20  20  (0)  0  40  30  0  0  0  0   .0125  0  0      0  0  20  0  0  (0)  0  20  0  0  0  0  0   .006  0  0  0  0  0  0  0      (0)  0  0  0  0  0  0  0  POST .1  70  40  20  20  60  40  40  (20)  0      30  0  20  0  80 100   .05  40  10  0  0  40  30  20  (0)  0  20  0  0      0  50 100   .0125  20  0  0  0  0  20  0  (0)  0  0  0   0  0  0  70      .012  0  0  0  0  0  0  0  (0)  0  0  0  0  0  0  40   .006  0  0  0  0      0  0  0  (0)  0  0  0  0  0  0  40 45 PRE .1  0  0  0  0  40  40  30      (0)  20  40  50  0  0  20  40   .05  0  0  0  0  40  0  0  (0)  0  0  0      0  0  0  20   .025  0  0  0  0  0  0  0  (0)  0  0  0  0  0  0  0      .0125  0  0  0  0  0  0  0  (0)  0  0  0  0   0  0  0   .006  0  0  0  0       0  0  0  (0)  0  0  0  0  0  0  0  POST .1  0  20  0  20  30  10  0      (0)  0  20  0  20  20  60  20   .05  0  0  0  0  0  0  0  (0)  0  0  0      0  0  40  0   .025  0  0  0  0  0  0  0  (0)  0  0  0  0  0  0  0      .0125  0  0  0  0  0  0  0  (0)  0  0  0  0  0  0  0   .006  0  0  0  0      0  0  0  (0)  0  0  0  0  0   0  0 50 PRE 1 100  50  40  60 100 100 100      100 100 100  90  30  60  90 100   .05 100  40  20  40 100 100  60  100      100 100  80  10  20  90  90   .025  50  20  0  30  90 100  30  90  80      60  80  0  0  50  60   .0125  30  0  0  0  50  70  0  65  80  40  60  0      0  20  30   .006  20  0  0  0  20  20  0  30  50  20  10  0  0  0  20      POST .1 100  90  40 100 100 100 100  100 100 100  70  60  40  80 100      .05 100  65  30  80  90 100 100  100  90 100   60  50  30  80 100   .025       90  50  20  40  90  90  55  90  40 100  50  20  20  70  60   .012  20      20  0  20  70  90  30  60  0 100  40  0  0  40  60   .006  10  0  0  0      40  65  0  50  0  60  30  0  0  30  40 51 PRE .1 100 100  70 100 100 100      100  100 100 100  70  60  80 100 100   .05 100  90  60  90 100  90 100      80 100  90  40  40  20  90 100   .025  50  70  30  60  90  90 100  80      100  90  30  20  20  90  70   .012  30  50  0  40  90  90  40  50  90      70  30  0  0  70  50   .006  0  30  0  30  50  80  20  40  70  50  0  0      0  70  20  POST .1 100 100  60 100 100 100 100  100 100 100  60  70 100      100 100   .05  80 100  40 100 100 100 100  100 100 100  50  80  70 100      100   .025  60 100  40  65  80 100 100  90  65 100  50  60  60 100  60      .012  40  90  30  50  70  70 100  90  40 100  40  65  20  60  50   .006      0  90  0  0  60  70  70  50  0 100  40  40  0  50  30 54 PRE 1 100 100      90  30 100 100 100  70 100 100  65  70  80  90 100   .05 100  90  70  20      100  90 100  50 100 100  60  65  65  90 100   .025 100  70  60  0  70      90  70  30 100  90  50  50  50  90  90   .012  40  40  0  0  50  70  50       0  70  20  50  0  0  80  50   .006  0  0  0  0  30  60  20   0  40  0      40  0  0   20  POST .1 100 100  70  50 100 100 100  100 100 100  60  90      80 100 100   .05 100 100  60  20 100 100  90  90  85 100  40  90  70 100       90   .025 100  75  50   0  90  90  80  70  60  80  30  90  50  70  60      .012  90  65  40  0  65  90  70  50  60  80  30  50  40  30  60   .006      60  40  20  0  30  90  50  30  10  50  30  50  20  30  50 55 PRE .1 100      100 100  40 100 100 100  65 100 100  70  70  70 100 100   .05 100  90      80  30 100  90 100  30 100  90  60  65  70 100  80   .025  60  80   0      100  80  70  30  90  50  60  50  60  90  90   .012  50  50  0  0  60  50       30   0  30  30  20  20   0  90  60   .006  30  40  0  0  20  20  0   0      0  10  0  0  0  90  0  POST .1 100 100  50  10 100  90 100  80 100 100      50 100 100 100 100   .05  90  90  40  0 100  90 100  70  30 100  40  90      70 100 100   .025  90  80  20  0  90  70  50  30  0  80  30  65  60 100      100   .012  40  70  20  0  50  70  50   0  0  80  30  40  20  60  20      .006  30  65  20  0  30  60  40   0  0  80  20  20  0  50  0 62 PRE 1      50  65  90  50 100 100  80  80  80 100  60  40  80  80 100   .05  40  50       60  40 100  90  70  70  60 100  40  30  70  80 100   .025  0  30  50  0       80  80  40  50  40 100  20  30  30  70 100   .012  0  20  20  0  60  50       20  40  30 100  20  10  20  65  80   .006  0  0  0  0  50  0  0  30  10       80  0  0  0  30  60  POST .1  40  80  70  60  95  70  90  70  90 100      40 100  30  75 100   .05  30  75  40  40  80  65  60  70  40 100  30  60       20   80   .025  10  70  30  20  60  60  40  40  40 100  20  40  10  0      65   .012  10  60  10  10  50  45  20  30  20 100  10  20  0   60   .006       0  40  0  10  40  20  0  10  0 100  0  0  0   20 64 PRE .1  10  40  50      0  65  60  40  60  50  80  40  65  40  90  90   .05  0  20  0  0  60  60       30  30  40  20  30  20  20  65  90   .025  0  0  0  0  30  30  10   0      0  0  20  0  0  0  80   .012  0  0  0  0  0  0  0   0  0  0  20  0  0  0       60   .006  0  0  0  0  0  0  0   0  0  0  10  0  0  0  40  POST .1  10      80  10  0  50  70  60  70  30 100  40 100  30  80  90   .05  0  80  10      0  40  70  40  65  30 100  40  90  20 100 100   .025  0  70  0  0  30      60  10  40  10 100  30  40  0  100   .012  0  70  0  0  20  40  0  30  0      100  20  10  0  30  40   .006  0  65  0   0  10  30  0  10  0  80  10  0       0   20 68 PRE 1  70  50  50  30 100  80  70  65  80 100  50  40  50  80      100   .05  50  40  50  0  70  50  60  50  65 100  50  0  30  50 100      POST .1  80  70  40  40  70  70  90  75  90 100  50  30  30  100   .05      50  50  20  10  60  60  65  65  80 100  30  0  10  60 100 76 PRE 1 100      0  30  30 100 100 100  (90) 100 100  60  0  0  20 100   .05  10  0  10      0  90 100  70  (90) 100 100  40  0  0  0  40   .025  50  0  0  0  40  80       50  (50) 100 100  30  0  0  0  10   .0125  0  0  0  0  0  50  30  (20)      40  90  0  0  0  0  0   .006  0  0  0  0  0  0  0  (0)  0   0  0  0  0      0  POST .1 100  40  0  30  70 100 100 (100) 100 100  60  20  0  20 100      .05 100  30  0  0  40  60 100  (80) 100  80  60  0  0  0  50   .025  80      0  0  0  0  40  40  (40)  80  20  60  0  0  0  40   .0125  0  0  0  0  0       0  0  (0)  20  0  30  0  0  0  10   .006  0  0  0  0  0  0  0  (0)  0      0  0  0  0  0  0 77 PRE .1 100  70  70  30 100 100 100 (100) 100 100  40       40  65  80 100   .05 100  50  60  10 100  80 100 (100) 100 100  30  10      0  40  70   .025  20  20  30  0  80  80 100  (65) 100 100  0  0  0  0      60  POST .1 100 100  40  0  60 100 100 (100) 100 100  60 100  60 100 100        .05 100 100  30  0  50 100 100 (100) 100 100  50  80  40 100 100      .025  40 100  20  0  50  40 100 (100)  50 100   30  65  0  0 100 80 PRE      .1 100  40  50  70 100 100 100 (100) 100 100  50  0  40 100 100   .05      60  30  30  40 100 100  70  (50) 100 100  30  0  0  50 100   .025  40  0       0  40  90  90  70  (40)  60 100  0  0  0  30 100  POST .1 100  40  0      70 100 100 100  (70) 100 100  0  65  20  40 100   .05 100  20  0  40  90      100 100  (60)  60 100  0  40  0  10 100   .025  40  0  0  0  60  40  60      (50)  50  60  0  20  0  0  60 81 PRE .1 100 100 100 100 100 100 100      (100) 100 100  60  90 100  80 100   .05 100 100 100 100 100 100 100      (100) 100 100  50  80 100  80 100   .025 100  90  90  70 100 100 100      (100) 100 100  50  50  90  70 100   .0125 100  70  65  40 100 100 100      (100) 100 100  0  40  50  50 100   .006  90  60  50  0 100  90 100  (70)      100 100  0  0  30  30 100  POST .1 100 100  70 100 100 100 100 (100) 100      100  0 100  60 100 100   .05 100  90  70  60 100 100 100 (100) 100 100      0 100  40  60 100   .025 100  70  50  50 100  50 100  (70) 100 100  0      90  30  30 100   .0125 100  50  20  40  90  40 100  (60) 100  80  0  70      0  0 100   .006 100  40  0  0  80  30  70  (60)  60  80  0  50  0  0  60      82 PRE 1 100 100 100  50 100 100 100 (100) 100 100   70  90  90 100      .05 100 100  90  10 100 100 100 (100) 100 100   40  50  80 100   .025      70  80  70  0 100  70 100  (90) 100 100   20  20  80 100   .0125  60  70       50  0 100  50  60  (60) 100 100   0  0  60  80   .006  30  50  40  0      50  30  40  (60) 100 100   0  0  40  40  POST .1  60 100  70  20  70 100      100 (100) 100 100  0 100  80  80 100   .05  50 100  50  0  60 100 100      (80) 100 100  0 100  70  30 100   .025  40 100  40  0  50  50 100  (50)      50 100  0  80  0  20  30   .0125  30  70  20  0  40  40 100  (50)  50      90  0  70  0  0  0   .006  0  50  0  0  40  40  70  (40)  40  80  0  60      0  0  0 86 PRE 1  0  0  0  0  40 100  70  (0)  80  65  50  0  40  30  0       .05  0  0  0  0  0  50  30  (0)  0  40  30  0  0  0  0 87 PRE 1  40  30       20  0  50  60  65  (40)  50  70  40  0  0  80  40   .05  10  0  0  0      20  30  40  (20)  20  60  0  0  0  60  20  POST .1  50  20  10  20  50      30  70  (40)  10  40  50  40  0  70  50   .05  20  10  0  0  20  20  0      (0)  0  0  0  0  0  40       0

    __________________________________________________________________________     PRIMARY SCREENING (PADDY SUBMERGED)- Herbicide                                               ORYSA                                                                               ORYSA                                                       Comp. No.                                                                            DAT kg/ha                                                                              (3 Leaf)                                                                            (seed)                                                                              ECHOR                                                                               SCPJU                                                                              MOOVA                                                                               CYPSE                                                                               SAGPY                               __________________________________________________________________________      1    2   .05  60   60   50   80  70  100   80                                  2    2   .05  60   70   60  100  90   90   90                                  3    3   .05  40   70   40   40  70   70   70                                 20    2   .1   90   80   80  100  90  100   80                                           .1  100   90  100  100 100  100  100                                           .05  90   90   80  100 100  100  100                                           .025                                                                                80   90   80  100 100  100   90                                           .012                                                                                70   60   70   90 100  100   80                                           .006                                                                                50   40   50   80  90   80   60                                 21    2   .05  30   50   50   70  70   90   80                                 22    2   .05  60   60   50   80  70   70   70                                 25    2   .05  50   70   60  100  90   80   90                                       3   .1   80  100  100  100 100  100  100                                           .05  80  100   90  100 100  100   10                                           .025                                                                                80  100   70  100  90  100  100                                           .012                                                                                80  100   60  100  90   90   90                                           .006                                                                                80  100   50   90  90   70   90                                 26    2   .05  60   90  100  100  90   70   70                                       3   .1   80  100  100  100 100  100  100                                           .05  80  100  100  100 100  100   90                                           .025                                                                                80  100   90  100 100  100   90                                           .012                                                                                80  100   80  100 100   90   90                                           .006                                                                                80  100   70  100 100   90   90                                 27    2   .05  90  100  100  100 100  100  100                                           .1  100  100  100  100 100       100                                           .025                                                                               100  100  100  100 100        90                                           .006                                                                               100   80   70  100 100        90                                           .0015                                                                               50   50   0    40 100        50                                           .0004                                                                               30   20   0    0   0         0                                  28    2   .05  90  100  100  100 100  100  100                                           .1  100  100  100  100 100        90                                           .025                                                                               100   90  100  100 100        70                                           .006                                                                                70   80   50   60  80        40                                           .0015                                                                               60   40   0    30  40        20                                 29    2   .05  60   80   70  100  90   40   90                                       3   .1   80  100  100  100 100   70  100                                           .05  80  100   80  100 100   60  100                                           .025                                                                                80  100   50  100  70   30  100                                           .012                                                                                50   30   0    50  50   0    80                                           .006                                                                                30   0    0    30  30   0    60                                 30    2   .05  60   80   70   90  90   40   90                                       3   .1   80  100  100  100 100   90  100                                           .05  80  100  100  100 100   80  100                                           .025                                                                                70  100   90  100 100   50  100                                           .012                                                                                60  100   10  100 100   40   90                                           .006                                                                                50  100   0    90  90   20   70                                 40    2   .05  50   40   0    20  0    30   0                                  42    2   .05  30   0    10   60  30   90   50                                 43    2   .05  0    0    0    0   30   0    0                                  44    2   .05  40   30   0    0   60   40   0                                  45    2   .05  60   60   40   50  60   80   60                                 46    2   .05  60   60   60   90  90    90  70                                       3   .1   90  100  100  100 100  100   90                                           .025                                                                                90   90   60  100  90  100   80                                           .006                                                                                40   70   50   60  50  100   60                                 47    2   .05  60   50   0    10  50   70   0                                  48    2   .05  60   50   20   50  60   40   0                                  49    2   .05  50   60       100  70   60   0                                        3   .1   80   90   80   80  70   80   70                                           .025                                                                                30   40   50   30  20   0    0                                            .006                                                                                0    0    10   0   0    0    0                                  50    1   .05  80   70   40   90  90   70   60                                 51    1   .05  70   80  100  100 100  100   90                                       2   .1  100  100  100  100 100  100  100                                           .025                                                                               100  100   90  100 100  100   90                                           .006                                                                                80   70   60  100  80   90   90                                           .0015                                                                               40   20   60   70  30   40   40                                 52    1   .05  70   80   70  100 100   90   70                                       3   .1   90  100  100  100 100  100   90                                           .025                                                                                80   90   80  100  80  100   80                                           .006                                                                                60   30   10   30  20   90   50                                 53    1   .05  60   70   50   90 100  100   40                                       2   .1   80   90   90  100  90  100   60                                           .025                                                                                50   30   40   60  70   80   20                                           .006                                                                                10   0    20   10  0    0    0                                  54    1   .05  80   90   60  100 100   50   90                                       2   .1   90  100   80  100 100   70   90                                           .025                                                                                80   70   50  100 100   50   80                                           .006                                                                                50   10   0    0   90   0    20                                 55    1   .05  70   70   50  100 100   60   60                                 56    2   .05  0    0    0    0   0    40   0                                  57    2   .05  60   60   80  100  80  100   90                                 58    2   .05  0    30   50   70  50   70   40                                       3   .5  100  100  100      100  100  100                                           .25  60   90  100      100  100  100                                           .125                                                                                40   65  100       90  100   85                                           .0625                                                                               30   30  100       90   90   80                                           .0312                                                                               0    0    90       90   90   75                                 59    2   .05  20   50   30   70  70   0    40                                 60    2   .05  0    0    40   20  40   0    0                                  61    2   .1   60   50   20   30  0    40   40                                 62    2   .1   70   60   70   90  80  100   80                                           .1   70   70   80  100 100  100  100                                           .05  70   60   50  100  20   70  100                                           .025                                                                                70   50   30   80  0    60   80                                           .012                                                                                40   30   0    60  0    30   60                                           .006                                                                                0    20   0    20  0    20   20                                 63    1   .05  70   70   20   70  40   40   80                                 64    2   .1   50   60   60   90  90   90   80                                           .1   70   80   70  100 100  100  100                                           .05  70   80   50  100 100  100  100                                           .025                                                                                70   70   10   90  60   60   90                                           .012                                                                                60   30   0    80  40   20   30                                           .006                                                                                30   20   0    80  0     0   30                                 65    2   .1   60   90   40   40  60   30   50                                 66    2   .1   50   60   30   40  50   30   50                                 68    2   .1   60   60   80   90  60   70   90                                 76    2   .05  60   50   20   40  40   50   0                                  77    2   .05  60   70   70   90  90   90   60                                       3   .1   90  100  100  100 100  100   90                                           .025                                                                                90   90   50  100 100  100   90                                           .006                                                                                60   80   20   80  60  100   90                                 78    2   .05  50   50   40   50  70   0    0                                  79    2   .05  40   50   10   30  40   30   0                                  80    2   .05  70   20   0    10  30   0    40                                 81    2   .05  60   50  100  100 100   60  100                                           .1   90  100  100      100        90                                           .025                                                                                90   70   90      100        90                                           .006                                                                                20   10   0        0         20                                 82    2   .05  80   90   90  100 100  100  100                                           .1  100  100  100      100       100                                           .025                                                                               100   90  100      100        80                                           .006                                                                                90   50   30       0         40                                 83    2   .05  60   50   60   30  40   70   50                                 84    2   .05  30   20   0    0   0    0    20                                 85    2   .05  10   10   20   40  70   0    0                                  86    2   .05  0    0    20   20  30   0    0                                  87    2   .05  0    0    0    0   0    0    0                                  88    2   .05  0    0    0    0   0    0    0                                  89    2   .05  0    0    0    0   0    0    0                                  __________________________________________________________________________

    __________________________________________________________________________     PRIMARY SCREENING (PADDY SUBMERGED)- Herbicide                                 Comp. No.                                                                            DAT kg/ha                                                                              ORYSA                                                                               ECHOR                                                                               SCPJU                                                                              BR.s                                                                              CYPSE                                                                               SAGPY                                      __________________________________________________________________________      4    2   .125                                                                                80   90   90  90                                                                               100   90                                                  .05  90  100  100 100                                                                               100  100                                                  .01  80   90  100  80                                                                               100  100                                                  .005                                                                                70   90  100  50                                                                               100  100                                         5    2   .125                                                                                70   80  100 100                                                                               100   90                                         6    2   .125                                                                                70   80   90  80                                                                                70   80                                         7    2   .125                                                                                80   90  100  90                                                                                50   70                                         8    2   .125                                                                                70   80  100  90                                                                                70  100                                         9    2   .125                                                                                40   40   40  50                                                                                20   40                                        10    2   .1   60   60  100  60                                                                                60   50                                        11    2   .1   40   40   0   70                                                                                60   60                                        12    2   .1   50   60   20   80                                                                              100   70                                        13    2   .125                                                                                40   50   30  30                                                                                70   50                                        14    2   .1   10   0    30  60                                                                                60   40                                        15    2   .1   30   0    20  60                                                                                40   30                                        16    2   .125                                                                                60   50   80  80                                                                                30   70                                        17    2   .125                                                                                0    30   70  50                                                                                40   60                                        18    2   .1   10   20   0   70                                                                                50   70                                        19    2   .1   90   90   90  90                                                                               100  100                                        23    2   .1   60   90  100 100                                                                               100  100                                        24    2   .1   50  100  100 100                                                                               100  100                                        31    2   .125                                                                                60   80   90  90                                                                                80   60                                        32    2   .125                                                                                10   60   70  70                                                                                40   50                                        33    2   .125                                                                                70  100  100 100                                                                               100   90                                        34    2   .125                                                                                90  100  100 100                                                                               100   80                                        35    2   .125                                                                                60   60   60  50                                                                                60   30                                        36    2   .125                                                                                40   30   50  60                                                                                60   30                                        37    2   .125                                                                                60  100  100 100                                                                                30   80                                        38    2   .125                                                                                50   60   90  80                                                                                60   70                                        39    2   .125                                                                                50   60  100  90                                                                                60  100                                        67    2   .1   40   50   40  40                                                                                70   60                                        68    2   .1   30   60   60  30                                                                                60   60                                        69    2   .1   70   60   50  50                                                                                60   70                                        71    2   .1   60   30   0   10                                                                                30   40                                        72    2   .1   50   20   50  40                                                                                40   40                                        73    2   .125                                                                                70  100   80  40                                                                                90   50                                        74    2   .125                                                                                70   90   60  50                                                                                0    80                                        75    2   .125                                                                                60   60   60  70                                                                                0    50                                        __________________________________________________________________________ 

What is claimed is:
 1. A compound of formula (I): ##STR146## wherein Q is Q-1, Q-2 or Q-3 are: ##STR147## wherein R¹ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, CN, NO₂, C₁ -C₃ alkoxy, C₁ -C₃ haloalkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃ alkysulfinyl, C₁ -C₃ alkylsulfonyl, SCHF₂, NH₂, NHCH₃, N(Me)₂, C₁ -C₂ alkyl substituted with C₁ -C₂ alkoxy, C₁ -C₂ haloalkoxy, SH, SCH₃, CN or OH; or CO₂ R^(III) ; wherein R^(I) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy; R^(II) is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, or when taken together connecting R^(I) and R^(II), --(CH₂)₃ --, (CH₂)₄ --, --(CH₂)₅ -- or CH₂ CH₂ OCH₂ CH₂ --, may be formed; R_(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₁ -C₄ alkyl substituted with 1˜3 halogens or cyano groups, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄ alkoxyalkyl;R is ##STR148## wherein, a is O or S; R² is C₁ -C₆ alkyl substituted with 1˜3 halogens; R⁴ and R⁵ are respectively C₁ -C₄ alkyl; and R₆ and R₇ are respectively H, C₁ -C₃ alkyl or C₁ -C₃ haloalkyl; E is CH₂ or single bond; R³ is H or CH₃ ; W is O or S; A is ##STR149## wherein, X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxylalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl ) amino or C₃ -C₅ cycloalkyl; Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₁ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl ) amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₁ -C₄ haloalkyl, C₂ -C₄ alkynyl, azido, cyano, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl CH₂ OH, C₃ -C₅ cycloalkyl, C₃ -C₅, cycloalkoxy, C₂ -C₅ alkylthioalkoxy, ##STR150## m is 2 or 3; L¹ and L² are independently O or S; R⁴ and R⁵ are independently C₁ -C₂ alkyl; R⁶ is H or CH₃ ; Z is N; X³ is CH₃ or OCH₃ ;or agriculturally suitable salts thereof.
 2. A compound as defined in claim 1, wherein W is O; E is single bond; and R³ is H.
 3. A compound as defined in claim 1, wherein R¹ is selected from the group consisting of H, halogen, C₁ -C₂ alkyl, C₁ -C₂ alkoxy, C₁ -C₂ haloalkyl, C₁ -C₂ alkylthio, haloalkoxy and CH₂ CN; X is selected from the group consisting of C₁ -C₂ alkyl, C₁ -C₂ alkoxy, Cl, F, Br, I, OCHF₂, CH₂ F, CF₃, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CH₂ Cl and CH₂ Br; and Y is H, C₁ -C₂ alkyl, C₁ -C₂ alkoxy, CH₂ OCH₃, CH₂ OCH₂ CH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ .tbd.CH, OCH₂ CH₂ OCH₃, CH₂ SCH₃, ##STR151## OCHF₂, OCF₂ Br, SCHF₂, cyclopropyl, C.tbd.CH or C.tbd.C--CH₃, and then R⁴ and R⁵ and C₁ -C₂ alkyl, R⁸ is H or CH₃, L¹ and L² are O or S, and m is 2 or
 3. 4. A compound as defined in claim 1, wherein A is A₁ ; X is CH₃, C₂ H₅, OCH₃, OCH_(2CH) ₃, Cl or OCHF₂ ; and Y is CH₃, OCH₃, OC₂ H₅, C₂ H₅, CH₂ OCH₃, NHCH₃, CH(OCH₃)₂ or cyclopropyl.
 5. A compound as defined in claim 1, wherein R² is CH₂ F, CH₂ CH₂ F, CHFCH₃, CH₂ Cl, CH₂ Br, CHCl₂, CHFCl, CH₂ CHCl, CHClCH₃, CHF₂, CHClCH₂ Cl, CHFCH₂ Cl, CHFCH₂ F or CH₂ CHF₂.
 6. A compound as defined in claim 1, wherein said general formula(I) is 3-(2-fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-methyltriazin-2-yl)aminocarbonyl]4-thiophenesulfonamide.
 7. A compound as defined in claim 1, wherein said general formula(I) is N-[(4,6-dimethoxytriazin-2-yl)aminocarbonyl]-3-(2-fluoromethyl-1,3-dioxalan-2-yl)-4-thiophenesulfonamide.
 8. A compound as defined in claim 1, wherein said general formula (I) is 2-(2-fluoromethyl-1,3-dioxalan-2-yl)-N-[(4-methoxy-6-methyltriazin-2-yl)aminocarbonyl]-3-thiophenesulfonamide.
 9. A compound as defined in claim 1, wherein said general formula(I) is N-[(4,6-dimethoxytriazin-2-yl)aminocarbonyl]-2-(2-fluoromethyl-1,3-oxalan-2-yl)-3-thiophenesulfonamide.
 10. An herbicidal composition comprising one or more compounds of formula (I) of claim 1 in combination with an inert carrier.
 11. A method of controlling weeds comprising applying an effective amount of one or more compounds of formula (I) of claim 1 to a weedy area. 